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Hirschprung\'s Disease. More than 50 years old since the discovery of the cause and the treatment for Hirschprung disease. Incidence : 1 in 5000 live birth80 % of patients are males. Hirschsprung Disease . Association with inheritance in chromosome 10 in some patients.RET- protooncogeneAutosomal dominant in totally agangloinic bowel.Common in Down syndrome.

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