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Available Medications for Treatment of Heroin Addiction. AgonistsOpiate Analgesics Methadone LAAMPartial Agonists BuprenorphineAntagonistsNaloxone (short-acting) Naltrexone (long-acting). How Does Buprenorphine Work?. High Affinity for Mu Opioid ReceptorCompetes with other opioids and blocks their effectsDisplaces heroin or other opiates from receptors (This can produce withdrawal if patient has opiates in system)Slow Dissociation from Mu Opioid ReceptorProlonged th23

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