Anesthesiology Anesthesia – is a reversible condition of comfort, quiescence and physiological stability in a patient before, during and after performance of a procedure. General anesthesia – for surgical procedure to render the patient unaware / unresponsive to the painful stimuli.
Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author.While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server.
Original in the Royal College of Surgeons of England, London.
Anesthetics are associated with
Hallmark of anesthesia:
General anesthetics have therapeutic indices of about 2 - 4.
It is the use of drugs prior to anesthesia to make it more safe and pleasant.
Stages of anesthesia:
behavior – dangerous state
respiratory and vasomotor
Molecular mechanism of the GA :
The main target of inhalation anesthetics is the brain.
There are two types of anesthetics :
Inhalational anesthetics :
The important characteristics of Inhalational anesthetics which govern the anesthesia are :
Blood : gas partition co-efficient:
Blood gas partition co-efficient affecting rate of induction and recovery
BLOOD GAS PARTITION COEFFICIENT
Oil: gas partition co-efficient:
Higher the Oil: Gas Partition Co-efficient lower the MAC . E.g., Halothane
Parenteral anesthetics (IV):
Ketamine : Dissociative anesthesia