Giving 5Fu in the home…. Safe handling practices for the patients and nurses . What is 5FU?. 5FU or 5-Fluorouracil is a chemotherapy drug that is cell cycle specific . Cell cycle specific means that the 5FU attacks cancer cells at a specific phase in cell division.
Safe handling practices for the patients and nurses
5FU or 5-Fluorouracil is a chemotherapy drug that is cell cycle specific. Cell cycle specific means that the 5FU attacks cancer cells at a specific phase in cell division.
Cell cycle non specific means that the chemo will work no matter where the cell is in it’s cell division process.
Most of our patients are getting a combination treatment most commonly called FOLFOX.
We administer 5Fu either by an Intermate
device or by Curlin pumps.
Most infusions go at a slow rate 2 to 10 mls. per hour over 46 hours on FOLOX regimen. Some patients receive a combination therapy that includes radiation Monday through Friday and continuous 5FU administered Monday through Friday for a 6 week course.
The radiation patients would then have a once a week bag change and line care (either PORT or PICC care) in the treatment room with their bag change.
A course of 5Fu treatment is given to patients for the treatment of GI cancers, such as colon/rectal, anal, esophageal, pancreatic, gastric and alsosome breast cancers. At DHCH, we see mostly GI cancers on 5FU. The typical course consists of IV therapy every 2 weeks for a total of 12 cycles.
Some patients may have chemotherapy pre-surgery for tumor reduction, then surgery for removal of tumor, then another course of chemotherapy post surgery to treat any remaining cancer. Some patients may not need surgery at all and still others may need radiation to shrink tumors. It’s all dependent on size, stage and type of cancer. 5FU treatment for GI cancer is what we typically see in the home.
The typical day of a 5FU patient starts with a PORT access, some patients may have a PICC line for chemo which they will keep for the duration of treatment. Then they go for a lab draw, current weight and calculation of the BSA.
They may or may not see the doctor. Then, based on labs, they may then get an infusion in clinic that could take up to 3-4hr to complete, then subsequent hook up by one of our infusion nurses to the 5FU, and then home. The patient will be hooked up to a continuous infusion of 5FU for the next 46 hours. Then after 46 hours the patient will need to be disconnected, flushed and de-accessed in the home (otherwise know as a “takedown”). That’s our part.
Hand Foot Syndrome
If patient is febrile greater 100.5* chills, sweats
CALL MD ASAP!!
Carry an extra container in your car in the event the yellow container is full. Switch out the full one for an empty one
Take the full container back to office and put it in the soiled utility room.
If you don’t have an extra container, call the office and schedule to have the full container picked up.
NEVER OVERFILL A CHEMO CONTAINER
www.chemocare.comCleveland Clinic Foundation
http://www.halls.md/body-surface-area/bsa.htm For body surface area