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FOGA “Round Table”

FOGA “Round Table”. Did we learn anything?. UNAM, Mexico 11/01/07. Genetic diversity. Real biological systems change through much richer mechanisms than we use in EC Can they be useful for us? In what areas? Combinatorial optimization? Should we try and model these? How?

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FOGA “Round Table”

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  1. FOGA “Round Table” Did we learn anything? UNAM, Mexico 11/01/07

  2. Genetic diversity • Real biological systems change through much richer mechanisms than we use in EC • Can they be useful for us? • In what areas? Combinatorial optimization? • Should we try and model these? How? • Why are they there in biology? This could indicate where to use them in EC. • Are they of interest in Genetics? How do they think they may be modeled?

  3. Modularity • There is complex cooperativity at all scales in living systems • This is not apparently present (not possibly present?) in EC or in Genetics. • Is it of any use in EC? Where? Combinatorial optimization? • How does one model so that it emerges without putting it in by hand? (epistasis induces correlation “by hand”).

  4. Representations • Why are representations (geno-pheno map) so exceedingly complex in biology? • Even the most GA-like systems in biology (RNA world) have complicated maps • Do we need them? (Neutrality etc.) • If so, in what areas? Combinatorial optimization? • How does Genetics deal with it?

  5. Mathematical modeling • Mathematical Modeling in EC and Genetics seems to be very similar (obviously?) • How to promote more transfer of knowledge? • Both “combinatorial optimization” – “GA” with a fixed fitness function(al) • How to do “real” calculations (numbers)? (Finite populations) • Why are the analogs of “practitioners” in genetics happier with theory than their EC colleagues? • Fitness – what is it good for? • Is it a barrier to “real evolution” as opposed to “breeding”

  6. Where to go? • Just forget about its biological origins? • E.g. Evolutionary strategies for combinatorial optimization? • Take them more seriously and take a more modern point of view? • What “problems/areas” need more “biology”? • Both? How much of each? • Supply/demand

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