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Exploring Recognition of Novel Objects in Generation X and Y Mice

This study examines the behavior of Generation X and Y mice in recognizing novel objects compared to non-displaced objects. It analyzes the latency to choose goal box, reward responses, and photobeam interactions. Generation differences in responses are explored through variables such as location latency and start box engagement. Supplementary figures provide visual representations of the findings.

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Exploring Recognition of Novel Objects in Generation X and Y Mice

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  1. a b -/- mkat-2 -/- Generation X 129 SvEv Generation X 129 SvEv mkat-2 FVB/N FVB/N wild-type wild-type -/+ -/+ -/+ -/+ mkat-2 mkat-2 mkat-2 mkat-2 -/- -/+ +/+ -/+ mkat-2 +/+ mkat-2 mkat-2 mkat-2 mkat-2 mkat-2 -/- X 11 Generations X 11 Generations -/- +/+ +/+ -/- mkat-2 mkat-2 mkat-2 mkat-2 Generation Y Generation Y Generation Y Generation Y Supplementary Figure 1

  2. S1 S2,S3,S4 S5,S6 S7 Non-Displaced objects (non-DOs) Displaced objects (DOs) Novel object for recognition (NO) Supplementary Figure 2

  3. Dependent Variables rf location non-rf location Latency to choose Goal box Goal box reward no reward Latency to rf location Latency to non-rf location Photobeams Latency to enter choice point Manual gates Latency to start Start box Supplementary Figure 3

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