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Outline. I. Introduction: Clinical Aspects of OSAA. Case scenarioB. Definition and epidemiologyC. Symptoms and signs D. Description of sleep apnea eventE. Diagnosis: polysomnographyII. Pathophysiology of OSAA. Mechanical/AnatomicB. Pulmonary1. Mechanics of breathing in OSA2. Effects of obstruction/apnea on gas exchangeC. Cardiovascular effects of OSA1. Effects on the pulmonary circulation2. Effects on the systemic circulationD. Disturbances in sleep architecture an20

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