D. Keane 2005. 2. Process Flow Overview cont\'d. IBTS/ Hospital Blood Bank Process Flow. Refer to Sequence 5 Acetate No. 9.. D. Keane 2005. 3. Process Flow Overview cont\'d QA Process Flow. How do we know when change happens?Need a mechanism to control change which will:-Identify proposed changeReview impact of change on the process flowReview requirement for validation based on change (method/ equipment).