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MMS’s Biotechnology Initiative The Gulf of Mexico OCS off Louisiana by Ken Turgeon Chief Scientist The Pacific OCS off southern California OCS Policy Committee meeting October 25, 2000 Genesis of MMS Biotechnology Research National Ocean Conference, June 11-12, 1998

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Presentation Transcript
slide1

MMS’s

Biotechnology

Initiative

The Gulf of Mexico OCS

off Louisiana

by

Ken Turgeon

Chief Scientist

The Pacific OCS off

southern California

OCS Policy Committee meeting

October 25, 2000

genesis of mms biotechnology research
Genesis of MMS Biotechnology Research
  • National Ocean Conference, June 11-12, 1998
    • Biotechnology is a major discussion topic
  • Turning to the Sea: America’s Ocean Future
    • Sept. 1999 Cabinet report to the President recommends biotechnology research and sustainable bioharvesting
  • Ocean Task Force -- created by Pres. Clinton
    • Adopts biotechnology as 1 of 11 key action items
    • MMS develops biotech. res. proj. for OTF consideration
    • OTF approves MMS plan -- sees it as cornerstone effort
    • MMS projects cited in the OTF’s report to the President

MMS

synopsis of mms research effort
Synopsis of MMS research effort
  • Determine taxonomic and genetic diversity found on offshore oil and gas platforms
  • Determine if selected organisms on platforms have compounds of potential application to pharmaceutical and other commercial uses
  • Rationale: platforms might serve as sites for harvesting marine bioproducts thus mitigating need to disturb natural ecosystems
  • Conduct research through LSU & UCSB CMIs
  • Each project is ~ $1 million total over 2 years;

co-funded equally by MMS and the States

MMS

slide4

CMI Biotechnology Research Teams

LSU UCSB

Dr. Larry Rouse 1 Dr. Russ Schmitt 1

Dr. Laurie Anderson Dr. Jennifer Dugan

Dr. Russ Chapman Dr. Scott Hodges

Dr. Dave Foltz Dr. Bob Jacobs

Dr. Mike Hellberg Dr. Henry Page

Dr. Fred Rainey Dr. Les Wilson

Dr. Barun Sen Gupta Dr. Steve Gaines

Dr. Suzanne Fredericq 2

1 CMI Director and Research Team Leader

2 University of Louisiana at Lafayette

MMS

mms biotechnology projects kick off
MMS Biotechnology Projects Kick-off
  • Signing ceremonies took place at LSU and UCSB on September 27, 2000
  • DOI officials attending UCSB signing:

-- David Hayes, Deputy Secretary

-- Bill Brown, Science Advisor to the Secretary

-- Tom Kitsos, MMS Deputy Director

-- Lisle Reed, MMS Pacific Regional Director

  • DOI officials attending LSU signing

-- Roger McManus, Ocean Advisor to the Secretary

-- Walt Rosenbusch, MMS Director

-- Chris Oynes, MMS Gulf of Mexico Regional Director

-- Ken Turgeon, Chief Scientist

MMS

some marine bioproducts of interest
Some Marine Bioproducts of Interest
  • Coumarins

-- combat tumor growth & promote wound healing

-- over 1,300 types found in terrestial organisms;

very few found to date in marine organisms

  • Eicosanoids

-- produced by unicell protists and chlorophytes

-- anti-inflammatories

  • Bryostatin

-- produced by symbiotic bacteria in bryozoans

-- combats growth of cultured cancer cells

-- cannot be synthesized yet (cost > $2,300/mg)

MMS

some marine bioproducts of interest7
Some Marine Bioproducts of Interest
  • Bacterial compounds

-- many potential pharmaceutical applications,

especially in area of antibiotics & enzymes

  • Bio-adhesives

-- found in attached & agglutinated organisms

-- foraminifera & mollusks will be investigated

MMS

slide9

Bryozoan

encrustation

on a

Gulf of Mexico

platform

MMS

slide10

Close-up views of

bryozoans

growing on

legs of oil and gas

platforms

MMS