Elizabeth Radke, MPH Faina Linkov, PhD University of Pittsburgh Cancer Institute. Background. Most commonly diagnosed cancer in American men Incidence rate=168.9 per 100,000 men Third most common cause of cancer death in the U.S. Mortality rate = 33.9 per 100,000 men
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Faina Linkov, PhD
University of Pittsburgh Cancer Institute
DETECTING PROSTATE CANCER
Kallikrein Tumor Markers
Digital Rectal Exam
STAGING PROSATE CANCER
The TNM staging system
Histologic Grading: The Gleason Score
Imaging Bone Metastases
Source: Surveillance, Epidemiology, and End Results Program, 1975-2000, Division of Cancer Control and Population Sciences, National Cancer Institute, 2003.
An antigen is something an antibody binds to.
Member of the Kallikrein protease family.
Vast majority of PSA in our body is produced by secretory prostate epithelial cells.
Also made in very low amounts in the breast, thyroid, and placenta, among others.