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Fruits and Vegetables and Ovarian Cancer Publication

Fruits and Vegetables and Ovarian Cancer Publication. Koushik, A., et al . Fruits and vegetables and ovarian cancer risk in a pooled analysis of 12 cohort studies. Cancer Epidemiol Biomarkers Prev 2005;14(9):2160-2167.

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Fruits and Vegetables and Ovarian Cancer Publication

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  1. Fruits and Vegetables and Ovarian Cancer Publication Koushik, A., et al. Fruits and vegetables and ovarian cancer risk in a pooled analysis of 12 cohort studies. Cancer Epidemiol Biomarkers Prev 2005;14(9):2160-2167.

  2. Cohort studies in the pooled analysis of fruits and vegetables and ovarian cancer Canadian National Breast Screening Study Swedish Mammography Cohort Netherlands Cohort Study Nurses’ Health Study, Nurses’ Health Study II, Women’s Health Study New York University Women’s Health Study New York State Cohort Total cohort size=560,441 Total # of cases = 2,130 Adventist Health Study Breast Cancer Detection Demonstration Project Follow-up Study Cancer Prevention Study II Nutrition Cohort Iowa Women’s Health Study

  3. Cohort studies in the pooled analysis of fruits and vegetables and ovarian cancer

  4. Median fruit and vegetable intakes (grams/day)

  5. Fruits and Vegetables and Ovarian Cancer: Pooled Multivariate RR by Quartile Quartile Total Fruits Total Veg. RR (95% CI) RR (95% CI) 1 1.00 1.00 2 1.07 (0.94-1.21) 1.07 (0.95-1.21) 3 1.05 (0.90-1.24)0.96 (0.85-1.09) 4 1.06 (0.92-1.21)0.90 (0.78-1.04) p for trend 0.73 0.06 p for het. for Q4 0.74 0.31

  6. Study-specific pooled multivariate RRs of ovarian cancer and fruit intake (Quartile 4 vs. 1)

  7. Study-specific pooled multivariate RRs of ovarian cancer and vegetable intake (Quartile 4 vs. 1)

  8. Pooled multivariate RRs of ovarian cancer and categories of fruit intake

  9. Pooled multivariate RRs of ovarian cancer and categories of vegetable intake

  10. Pooled multivariate RRs of ovarian cancer and botanically defined groups Group RR (95% CI) Compositae 0.86 (0.74-1.01) Cruciferae 0.95 (0.82-1.11) Cucurbitaceae 1.07 (0.83-1.37) Leguminosae 0.90 (0.75-1.09) Rosaceae 1.02 (0.96-1.07) Rutaceae 0.99 (0.95-1.03) Solanacea 0.94 (0.87-1.03) Umbelliferae 0.96 (0.77-1.18)

  11. Pooled multivariate RRs of ovarian cancer and specific fruits Food Weight of RR (95% CI) one serving Apples, pears 138 g 1.03 (0.93-1.13) Bananas 114 g 1.04 (0.90-1.20) Cantaloupe 134 g 1.55 (0.77-3.10) Grapefruit 120 g 1.00 (0.87-1.15) Oranges 131 g 0.98 (0.83-1.15) Peaches 87 g 1.00 (0.85-1.17) Fruit juices 190 g 0.99 (0.92-1.06) Increment = 1 serving/day

  12. Pooled multivariate RRs of ovarian cancer and specific vegetables Food Weight of RR (95% CI) one serving Broccoli 78 g 0.89 (0.68-1.17) Brussels sprouts 78 g 1.01 (0.61-1.67) Cabbage 68 g 1.01 (0.76-1.33) Carrots 57 g 1.02 (0.86-1.20) Lettuce, Salad 56 g 0.93 (0.85-1.02) Peas, lima beans 80 g 1.17 (0.83-1.64) String beans 68 g 0.82 (0.52-1.30) Spinach 73 g 1.01 (0.83-1.23) Tomatoes, tomato juice 122 g 0.91 (0.77-1.07) Yams, sweet potatoes 128 g 1.08 (0.48-2.42) Increment = 1 serving/day

  13. Pooled multivariate RRs of ovarian cancer and fruits and vegetables by histology Histological RR (95% CI) p-value for type interaction Total fruits All histologies 1.00 (0.97-1.02) Serous 1.01 (0.97-1.04) Endometrioid 1.01 (0.94-1.08) 0.81 Mucinous 1.03 (0.93-1.14) Total vegetables All histologies 0.98 (0.94-1.01) Serous 0.98 (0.91-1.05) Endometrioid 1.06 (0.96-1.18) 0.16 Mucinous 1.10 (0.94-1.27)

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