Anything that you want to know about troponins but never ask. Thao Huynh & Roland Sabbagh Division of Cardiology MUHC. WHO classification of MI. 2/3 these criteria: Ischemic symptoms EKG changes. Increased serum markers. CPK-MB. 15% of cardiac CPK, small amount in skeletal muscle
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Thao Huynh & Roland Sabbagh
Division of Cardiology
2/3 these criteria:
Actin and tropomyosin
Same isoform for both skeletal and cardiac muscles.
7 clinical trials and 19 cohort studies:
For death & MI:
Each point scores 1.
Intermediate:3-4 (14-days events:13-20%).
High: 6-7 (14-days events: 40%).
Myocardial infarction: elevation of serum troponin T/I >0.1.
733 patients Troponins T & I