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30:1 Adv0 - PowerPoint PPT Presentation


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Figure 1. A. B. C. Uninfected 3:1 10:1 30:1 60:1. Uninfected 10:1 30:1 60:1. 30:1 Adv0. 30:1 AdvGFP. Figure 2. Cytosolic I B p42/44 MAP kinases NF B activation on EMSA. Uninf AdvI B Adv0. Figure 3. Adv0. 180. 160. AdvI B. 140. 120. 100. % production.

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Presentation Transcript
slide1

Figure 1

A

B

C

Uninfected

3:1

10:1

30:1

60:1

Uninfected

10:1

30:1

60:1

30:1 Adv0

30:1 AdvGFP

slide2

Figure 2

Cytosolic IB

p42/44 MAP kinases

NFB activation on EMSA

Uninf AdvIB Adv0

slide3

Figure 3

Adv0

180

160

AdvIB

140

120

100

% production

80

60

40

20

0

TNF

IL-1

IL-10

Cytokine

slide4

Figure 4

Adv0

140

AdvIB

120

100

80

% production

60

40

20

0

IL-6

IL-8

MCP-1

OnST-M

GM-CSF

Cytokine

slide5

IL-11

IL-1 RA

p55sTNF-R

p75sTNF-R

Figure 5

Adv0

120

AdvIB

100

80

% production

60

40

20

0

Cytokine

slide6

Figure 6

160

Adv0

140

AdvIB

120

100

% production

80

60

40

20

0

MMP-1

MMP-3

MMP-9

MMP-13

TIMP-1

slide7

Figure 7

TNF +

Cycloheximide

AdvIkBa

Treatment

AdvO

0

0.0

0.5

1.0

1.5

2.0

2.5

3.0

3.5

Caspase Ratio

E

A

B

C

D

slide8

Figure 8

A

B

Uninfected

Uninfected

Adv0

Adv0

AdvIB

AdvIB