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Visit here: https://www.edhacare.com/treatments/organ-transplant/bone-marrow <br><br><br>A bone marrow transplant involves collecting healthy stem cells and transplanting them to replace unhealthy blood-forming cells. The procedure includes health assessment, stem cell collection, body preparation with chemotherapy/radiation, stem cell injection, hospital stay for recovery, different types of transplants (autologous and allogeneic), and post-transplant care to prevent infections and monitor health. Risks include fatigue, pain, rejection, and GVHD. Seek emotional support to cope with the transplant.
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1 Bone Marrow Transplant Procedure Website: https://www.edhacare.com/ E-mail: care@edhacare.com
2 Table Of Content ● Introduction ● Types of Bone Marrow Transplant ● Pre-Transplant Preparation ● Bone Marrow Transplant Procedure ● Stem Cell Collection (Harvesting) ● Transplanting the Stem Cells ● Post-Transplant Recovery ● Complications & Success Rate ● Conclusion https://www.edhacare.com/treatments/organ-transplant/bone-marrow
3 Bone Marrow Transplantation A bone marrow transplant, also known as a stem cell transplant, is a medical procedure that replaces damaged or destroyed bone marrow with healthy bone marrow. Used to treat blood cancers (leukemia, lymphoma) and other disorders (aplastic anemia, SCID, etc.) https://www.edhacare.com/treatments/organ-transplant/bone-marrow 3
4 Types of Bone Marrow Transplant Umbilical Cord Blood Transplant Autologous Transplant Allogeneic Transplant Uses stem cells from umbilical cord blood Stem cells from a donor (matched sibling/unrelated donor) Patientʼs own stem cells are used https://www.edhacare.com/treatments/organ-transplant/bone-marrow
5 Pre-Transplant Preparation Before the transplant, the recipient undergoes "conditioning," which involves: Patient Evaluation – Blood tests, imaging, organ function tests Finding a Donor – HLA matching for allogeneic transplant Conditioning Regimen – High-dose chemotherapy and/or radiation to destroy diseased bone marrow Suppression of the immune system to prevent rejection of the transplanted stem cells. ● ● ● ● 5 https://www.edhacare.com/treatments/organ-transplant/bone-marrow
Bone Marrow Transplant Procedure 6 Step 1 Collection of stem cells (from donor or patient) Step 2 Stem cell processing and storage Step 3 Infusion of stem cells via IV (similar to a blood transfusion) Step 4 Engraftment – New stem cells begin producing healthy blood cells https://www.edhacare.com/treatments/organ-transplant/bone-marrow
7 Stem Cell Collection Harvesting) ● Bone Marrow Harvest: Stem cells are collected from the donor's bone marrow, usually from the hip bones. The procedure is performed under anesthesia. ● Peripheral Blood Stem Cell Collection (Apheresis): The donor receives medications to stimulate stem cell production. Blood is drawn, and a machine separates the stem cells, returning the remaining blood to the donor. ● Cord Blood Transplant: Stem cells are collected from umbilical cord blood after a baby's birth https://www.edhacare.com/treatments/organ-transplant/b one-marrow
8 Transplanting the Stem Cells The collected stem cells are infused into the recipient's bloodstream through a central venous catheter. This process is similar to a blood transfusion. The stem cells then travel to the bone marrow, where they begin to produce new blood cells. https://www.edhacare.com/treatments/organ-tran splant/bone-marrow 8
9 Post-Transplant Recovery Project Timeline The recovery period is crucial, as the recipient's immune system is weak. Q1 JANMAR Q2 APRJUN Q3 JULSEPT Patients are monitored closely for infections and other complications. "Engraftment" occurs when the transplanted stem cells begin to produce new blood cells. This process can take several weeks. Q4 OCTDEC ● ● Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. ● Post transplant care can last for many months, and even years, as the patient recovers. ● https://www.edhacare.com/treatments/organ-transplant/bone-marrow
10 Complications & Success Rate Allogeneic transplants with matched related donors achieve the highest success rates 7090%. Using a 10/10 match from an unrelated donor yields a 87.7% survival rate, while 9/10 matches result in 76% survival. Unrelated donors see success rates of 3665%. Autologous transplants have success rates of 5080%. ● Short-term: Infections, nausea, bleeding, mucositis (mouth sores) Long-term: Graft-versus-host disease GVHD, organ damage, secondary cancers ● ● ● ● ● https://www.edhacare.com/treatments/organ-transplant/bone-marrow
Conclusion 11 Bone Marrow Transplant (BMT) treats blood disorders like leukemia. Types include Autologous, Allogeneic, and Umbilical Cord Blood Transplant. Procedure involves conditioning, stem cell infusion, and recovery. Risks include infections, GVHD, and need for careful follow-up. Medical research advances improve outcomes. Bone marrow transplantation offers a second chance at life, but it requires proper medical care, donor compatibility, and post-transplant monitoring for the best outcomes. https://www.edhacare.com/treatments/organ-transplant/bone-marrow
https://www.edhacare.com/treatments/organ-transplant/bone-marrowhttps://www.edhacare.com/treatments/organ-transplant/bone-marrow