Imatinib Tablets IP 400 mg: What Patients Should Know Before Starting Treatment

1. Imatinib Tablets IP 400 mg: What Patients Should Know Before Starting Treatment Imatinib Tablets IP 400 mg have revolutionized the treatment landscape for certain types of cancers, especially chronic myeloid leukemia (CML) and gastrointestinal stromal tumors (GISTs). These targeted therapy drugs belong to a class called tyrosine kinase inhibitors, which work by blocking specific enzymes that promote the growth of cancer cells. At Oddway International, a trusted name in wholesale Specialty Pharmacy, we provide both bulk and retail supply of Imatinib 400 mg tablet to healthcare providers, pharmacies, hospitals, and individual buyers. As a key player in the supply chain for prescription medications and wholesale medical supplies, we offer prompt delivery, international reach, and top-notch quality standards for every product we distribute. This comprehensive guide is designed to educate patients, caregivers, and healthcare professionals about Imatinib Tablets IP 400 mg – how they work, what to expect, potential side effects, and where to source them reliably. What is Imatinib 400 mg tablet and How Does It Work? Understanding the Drug Class

2. Tyrosine kinase inhibitors include imatinib 400 mg tablets, sometimes referred to as imatinib mesylate. This means it interferes with the action of enzymes (kinases) that are involved in the growth and proliferation of cancer cells. Mechanism of Action The drug targets the BCR-ABL protein, a product of a chromosomal abnormality found in CML patients known as the Philadelphia chromosome. Imatinib 400 mg tablet binds to this protein and prevents it from sending signals that promote the growth of leukemic cells. In GIST, Imatinib targets c-KIT (CD117), a receptor tyrosine kinase that contributes to tumor growth. By inhibiting this receptor, the drug helps shrink or stabilize tumors. Indications: Who Needs Imatinib Tablets IP 400 mg? Imatinib 400 mg tablet is prescribed for the treatment of: ● Chronic Myeloid Leukemia (CML) ● Acute Lymphoblastic Leukemia (ALL) with Philadelphia chromosome ● Gastrointestinal Stromal Tumors (GIST) ● Systemic Mastocytosis ● Hypereosinophilic Syndrome (HES) and/or Chronic Eosinophilic Leukemia (CEL) ● Dermatofibrosarcoma Protuberans (DFSP) Approved Uses by Regulatory Authorities Imatinib 400 mg tablet are approved by major regulatory bodies like the FDA, EMA, and CDSCO (India), and widely used across global healthcare systems. Dosage and Administration Typical Dosage Regimens ● CML (Chronic Phase): Imatinib 400 mg tablet once daily ● CML (Accelerated/Blast Phase): 600–800 mg daily (split doses) ● GIST: 400–600 mg daily depending on tumor response ● Pediatric Patients: Dosage based on body surface area How to Take Imatinib 400 mg tablet ● Take with a meal and a full glass of water to avoid gastrointestinal irritation. ● Do not crush, break, or chew the tablet. ● Take the medicine at the same time every day for best results. Potential Side Effects and Risks

3. Like all medications, Imatinib Tablets IP 400 mg may cause side effects. These can vary based on individual health status and concurrent medications. Common Side Effects of Imatinib 400 mg tablet ● Nausea, vomiting ● Muscle cramps ● Diarrhea ● Fatigue ● Swelling (especially around the eyes and ankles) ● Skin rash ● Headache Serious Side Effects (Seek Medical Attention) ● Severe fluid retention ● Liver toxicity (jaundice, dark urine) ● Low blood cell counts (infections, bleeding, anemia) ● Heart problems (chest pain, irregular heartbeat) ● Gastrointestinal bleeding Precautions Before Starting Imatinib 400 mg tablet Before starting treatment with Imatinib tablets IP 400 mg, inform your healthcare provider if you: ● Have liver, kidney, or heart disease ● Are taking other medications, especially those affecting liver enzymes ● Have had a history of gastrointestinal bleeding Drug Interactions Imatinib may interact with a wide range of medications, including: ● Warfarin and anticoagulants ● CYP3A4 inhibitors (like ketoconazole, erythromycin) ● CYP3A4 inducers (like rifampin, phenytoin) ● St. John’s Wort ● Acetaminophen (in large doses) To ensure safe treatment, provide a full list of medications to your healthcare provider. Monitoring and Follow-up During Treatment

4. Regular monitoring is essential to ensure the effectiveness of Imatinib 400 mg tablet and to manage any adverse reactions. Monitoring includes: ● Complete blood counts (CBC) ● Liver function tests ● Kidney function ● BCR-ABL gene levels (in CML) ● Tumor response (in GIST) Managing Side Effects Side effects can often be managed with supportive medications or dose adjustments. ● Nausea: Antiemetic drugs ● Edema: Diuretics and reduced salt intake ● Rashes: Topical steroids or antihistamines ● Fatigue: Balanced nutrition, rest, and hydration Pregnancy and Breastfeeding Considerations Imatinib can harm a developing fetus. Women of childbearing age should: ● Use effective contraception ● Avoid pregnancy during and for several months after treatment Breastfeeding is not recommended as the drug can pass into breast milk. Patient Lifestyle and Dietary Tips While on Imatinib 400 mg tablet, maintaining a healthy lifestyle can boost treatment effectiveness. Tips: ● Eat small, frequent meals to manage nausea ● Avoid grapefruit and grapefruit juice ● Limit alcohol intake ● Stay hydrated ● Practice good hand hygiene to avoid infections Long-Term Use of Imatinib 400 mg tablet For many CML patients, Imatinib Tablets IP 400 mg become a lifelong therapy. Long-term use has shown positive results in maintaining remission, with manageable side effects.

5. Doctors may occasionally reduce the dosage or consider discontinuation in patients who have achieved deep molecular remission for several years. 12. Storage and Handling ● Store at room temperature (20–25°C) ● Keep away from moisture, heat, and direct light ● Keep out of reach of children ● Do not use after the expiry date Cost and Accessibility The cost of Imatinib 400 mg tablet can vary widely depending on the manufacturer, country of purchase, and healthcare system. Oddway International helps bridge the gap by offering affordable pricing for: ● Hospitals and clinics ● Pharmacies and retail chains ● NGOs and humanitarian organizations ● Patients and caregivers We supply both generic and branded versions of Imatinib 400 mg tablet, ensuring you receive trusted quality at competitive rates. Why Choose Oddway International? As a globally recognized pharmaceutical wholesaler, Oddway International is committed to providing high-quality prescription medications and medical supplies across continents. We specialize in Imatinib 400 mg tablet, with a focus on: ● Bulk orders and retail quantities ● International shipping ● Genuine products from licensed manufacturers ● Competitive wholesale pricing ● Reliable supply chain and logistics Key Highlights ● GMP and WHO-GDP compliance ● End-to-end export documentation ● Secure packaging and timely delivery ● Dedicated customer support Purchasing Imatinib Tablets IP 400 mg from Oddway International

6. Whether you are a healthcare facility, pharmacy, medical distributor, or individual seeking access to life-saving medications, Oddway International ensures a smooth ordering experience. We make it easy to order Imatinib 400 mg tablet in bulk or retail quantities from anywhere in the world. Our logistics network supports shipping to over 150 countries, with secure packaging and all required documentation. Contact us today to place your order and join thousands of global customers who trust Oddway International for their pharmaceutical needs. Conclusion Imatinib Tablets IP 400 mg have transformed the management of cancers like CML and GIST by offering targeted, effective treatment with manageable side effects. As a trusted therapy, its impact on patient outcomes has been revolutionary. At Oddway International, we’re proud to support global healthcare by providing access to high-quality Imatinib 400 mg tablet through our robust distribution channels. Whether you’re looking to order Imatinib Tablets IP 400 mg for clinical use, pharmacy shelves, or individual treatment, we’re here to ensure timely, secure, and affordable delivery. Oddway International – Your Global Partner in Pharmaceutical Excellence Delivering prescription medications, wholesale medical supplies, and retail pharmaceutical products – with quality you can trust and service you can count on. Place your order for Imatinib 400 mg tablet today. Original Source : Imatinib Tablets IP 400 mg: What Patients Should Know Before Starting Treatment