Defining Endpoints for Recurrence in Randomised Controlled Trials of Systemic Therapy for Early Breast Cancer: A Call fo Preloader

Defining Endpoints for Recurrence in Randomised Controlled Trials of Systemic Therapy for Early Breast Cancer: A Call fo - PowerPoint PPT Presentation


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Recurrence-related endpoints. . Four most used recurrence endpoints in early breast cancer:Disease Free Survival (DFS)Recurrence Free Survival (RFS)Event Free Survival (EFS)Time to Recurrence (TTR)Usually composites of two or more of the following events:Local Recurrence (LR)Distant Recurrence (DR)Contralateral breast cancer (CLB)Non breast second primary (NBSP)Breast cancer death (BC death)Death - any cause.

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