2004 2005 chemotherapeutics review l.
Download
Skip this Video
Loading SlideShow in 5 Seconds..
2004-2005 Chemotherapeutics Review PowerPoint Presentation
Download Presentation
2004-2005 Chemotherapeutics Review

Loading in 2 Seconds...

play fullscreen
1 / 192

2004-2005 Chemotherapeutics Review - PowerPoint PPT Presentation


  • 198 Views
  • Uploaded on

2004-2005 Chemotherapeutics Review. 10 March 2014 12:05 PM. Abacavir. Antiretroviral Nucleoside reverse transcriptase inhibitor (NRTI). Acyclovir. Antiherpes Purine analog Phosphorylated to inhibitor of viral DNA polymerase. Albendazole. Antihelminthic Treatment of intestinal roundworms.

loader
I am the owner, or an agent authorized to act on behalf of the owner, of the copyrighted work described.
capcha
Download Presentation

PowerPoint Slideshow about '2004-2005 Chemotherapeutics Review' - niveditha


An Image/Link below is provided (as is) to download presentation

Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author.While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server.


- - - - - - - - - - - - - - - - - - - - - - - - - - E N D - - - - - - - - - - - - - - - - - - - - - - - - - -
Presentation Transcript
abacavir
Abacavir
  • Antiretroviral
  • Nucleoside reverse transcriptase inhibitor (NRTI)
acyclovir
Acyclovir
  • Antiherpes
  • Purine analogPhosphorylated to inhibitor of viral DNA polymerase
albendazole
Albendazole
  • Antihelminthic
  • Treatment of intestinal roundworms
alemtuzumab
Alemtuzumab
  • Antineoplastic
  • Anti-CD52 antibody
amantadine
Amantadine
  • AntiviralAntiparkinson
  • Treatment of Influenza A Inhibits replicationat the stage of uncoating
amikacin
Amikacin
  • Aminoglycoside antibioticBactericidal protein synthesis inhibitor
  • 30S ribosomeFreezes initiation
aminoglutethimide
Aminoglutethimide
  • AntineoplasticImmunosuppressive
  • Glucocorticoid antagonistAromatase inhibitor(decreases steroid synthesis)
aminoglycosides
Aminoglycosides
  • AntibioticsBactericidal protein synthesis inhibitors
  • 30S ribosomeFreeze initiation
ampicillin
Ampicillin
  • Penicillin antibioticCell wall synthesis inhibitor
  • Amino penicillinInhibits peptidoglycan cross-linking
amphotericin b
Amphotericin B
  • AntifungalPolyene antibiotic
  • Binds to ergosterol and alters permeabilitySystemic
amsacrine
Amsacrine
  • Antineoplastic
  • Miscellaneous
anastrozole
Anastrozole
  • AntineoplasticAntiestrogen
  • Aromatase inhibitor
anti thymocyte globulin
Anti-thymocyte globulin
  • Immunosuppressive
  • Anti-T cell antibody
arsenicals
Arsenicals

Melarsoprol

  • Tropical antiparasitic
  • Treatment of African Trypanosomiasis in CNS
l asparaginase
L-asparaginase
  • Antineoplastic
  • Protein synthesis inhibitor
atovaquone
Atovaquone
  • Antimalarial
  • Depolarizes parasitic mitochondria and inhibits electron transport
azathioprine
Azathioprine
  • ImmunosuppressiveAntineoplastic
  • Antimetabolite(“pseudofeedback inhibition” of HGPRT and PRP)
azithromycin
Azithromycin
  • Macrolide antibioticBacteriostatic protein synthesis inhibitor
  • 50S ribosome Inhibits translocation
aztreonam
Aztreonam
  • New b lactam antibiotic
  • Monobactam
bacitracin
Bacitracin
  • AntibioticCell wall synthesis inhibitor
  • Topical, not a b lactam, Inhibits dephosphorylation of bactoprenol
basiliximab
Basiliximab
  • Immunosuppressive
  • Anti-CD25 (interleukin 2 receptor) Organ transplant (antirejection)
benzathine penicillin g
Benzathine penicillin G
  • Penicillin antibioticCell wall synthesis inhibitor
  • Inhibits peptidoglycan cross-linking Repository preparation
bleomycin
Bleomycin
  • Antineoplastic
  • Natural productAntibiotic
busulfan
Busulfan
  • Antineoplastic
  • Alkylating Agent
carbenicillin
Carbenicillin
  • Penicillin antibioticCell wall synthesis inhibitor
  • Anti-pseudomonal penicillinInhibits peptidoglycan cross-linking
carmustine bcnu
Carmustine (BCNU)
  • Antineoplastic
  • Alkylating Agent
cefaclor
Cefaclor
  • Cephalosporin antibioticCell wall synthesis inhibitor
  • 2nd generationOral
cefadroxil
Cefadroxil
  • Cephalosporin antibioticCell wall synthesis inhibitor
  • 1st generationOral
cefepime
Cefepime
  • Cephalosporin antibioticCell wall synthesis inhibitor
  • 4th generationCSF penetration
cefotaxime
Cefotaxime
  • Cephalosporin antibioticCell wall synthesis inhibitor
  • 3rd generationCSF penetration
cefoxitin
Cefoxitin
  • Cephalosporin antibioticCell wall synthesis inhibitor
  • 2nd generation
ceftazidime
Ceftazidime
  • Cephalosporin antibioticCell wall synthesis inhibitor
  • 3rd generation
ceftriaxone
Ceftriaxone
  • Cephalosporin antibioticCell wall synthesis inhibitor
  • 3rd generationCSF penetration
cefuroxime
Cefuroxime
  • Cephalosporin antibioticCell wall synthesis inhibitor
  • 2nd generationCSF penetration
cephalexin
Cephalexin
  • Cephalosporin antibioticCell wall synthesis inhibitor
  • 1st generationOral
cephalosporins
Cephalosporins
  • Antibioticsb lactam
  • Cell wall synthesis inhibitorsInhibit cross-linking of peptidoglycan
cephalothin
Cephalothin
  • Cephalosporin antibioticCell wall synthesis inhibitor
  • 1st generationOral
chloramphenicol
Chloramphenicol
  • AntibioticBacteriostatic protein synthesis inhibitor
  • 50S ribosomeInhibits peptide bond formation
chloroquine
Chloroquine
  • Antimalarial
  • Intercalates in DNABinds to ferriprotoporphyrin
cidofovir
Cidofovir
  • Antiherpes
  • Pyrimidine analogPhosphorylated to inhibitor of viral DNA polymerase
ciprofloxacin
Ciprofloxacin
  • Fluoroquinolone antibioticDNA replication inhibitor
  • Inhibits bacterial DNA gyrase
cisplatin
Cisplatin
  • Antineoplastic
  • MiscellaneousCross-linking agent
clarithromycin
Clarithromycin
  • Macrolide antibioticBacteriostatic protein synthesis inhibitor Antiulcer
  • 50S ribosomeInhibits translocation
clavulanic acid
Clavulanic acid
  • b-lactamase inhibitor
  • Combined with antibacterials
clindamycin
Clindamycin
  • AntibioticBacteriostatic protein synthesis inhibitor
  • 50S ribosomeAnaerobic infections
clotrimazole
Clotrimazole
  • Imidazole antifungal
  • Inhibits synthesis of ergosterolLanosterol 14a demethylase inhibitor
cloxacillin
Cloxacillin
  • Penicillin antibioticCell wall synthesis inhibitor
  • Penicillinase resistant penicillinInhibits peptidoglycan cross-linking
cyclophosphamide
Cyclophosphamide
  • Antineoplastic
  • Alkylating Agent
cycloserine
Cycloserine
  • AntibioticCell wall synthesis inhibitor
  • Secondary TB drugInhibits formation of Park nucleotide
cyclosporine
Cyclosporine
  • ImmunosuppressiveAntineoplastic
  • Binds cyclophilinInhibits calcineurin
cyproterone acetate
Cyproterone acetate
  • AntiandrogenAntineoplastic
  • androgen receptor antagonist
cytarabine arac
Cytarabine (AraC)
  • Antineoplastic
  • Antimetabolite
dacarbazine
Dacarbazine
  • Antineoplastic
  • Alkylating Agent
daclizumab
Daclizumab
  • Immunosuppressive
  • Anti-CD25 (interleukin 2 receptor) antibody Organ transplant (anti-rejection)
dactinomycin
Dactinomycin
  • Antineoplastic
  • Natural productAntibiotic
dapsone
Dapsone
  • Sulfone antibioticNucleic acid andprotein synthesis inhibitor
  • Inhibits dihydropteroate synthetaseLeprosy
daunorubicin
Daunorubicin
  • Antineoplastic
  • Anthracycline antibiotic Natural product
delavirdine
Delavirdine
  • Antiretroviral
  • Non-nucleoside reverse transcriptase inhibitor (NNRTI)
dexamethasone
Dexamethasone
  • AdrenocorticosteroidGlucocorticoidAntineoplastic
  • Anti-inflammatory steroidNot by inhalation
didanosine
Didanosine
  • Antiretroviral
  • Nucleoside reverse transcriptase inhibitor (NRTI) Dideoxyinosine (ddI)
diethylcarbamazine
Diethylcarbamazine
  • Antihelminthic
  • Treatment of intestinaland tissue roundworms
doxorubicin
Doxorubicin
  • Antineoplastic
  • Anthracycline antibioticNatural product
doxycycline
Doxycycline
  • Tetracycline antibioticBacteriostatic protein synthesis inhibitor
  • 30S ribosomePrevents aminoacyl tRNA attachment
efavirenz
Efavirenz
  • Antiretroviral
  • Non-nucleoside reversetranscriptase inhibitor (NNRTI)
enfuvirtide t 20
Enfuvirtide (T-20)
  • Antiretroviral
  • Fusion inhibitor
erythromycin
Erythromycin
  • Macrolide antibioticBacteriostatic protein synthesis inhibitor
  • 50S ribosomeInhibits translocation
ethambutol
Ethambutol
  • Antibiotic
  • Major drug for tuberculosis
ethionamide
Ethionamide
  • Antibiotic
  • Secondary drug for tuberculosis
etoposide
Etoposide
  • Antineoplastic
  • Natural productPlant alkaloid
exemestane
Exemestane
  • AntineoplasticAntiestrogen
  • Aromatase Inhibitor
famciclovir
Famciclovir
  • Antiherpes
  • Purine analogPhosphorylated to an inhibitor ofviral DNA polymerase
fluconazole
Fluconazole
  • Triazole antifungal
  • Inhibits synthesis of ergosterol by inhibiting lanosterol 14a demethylase
flucytosine
Flucytosine
  • Antifungal
  • Converted by fungi to 5-fluorouracil  faulty RNA and DNA synthesis
fluorinated quinolones ciprofloxacin norfloxacin
Fluorinated Quinolonesciprofloxacin, norfloxacin
  • AntibioticsDNA replication inhibitors
  • Inhibit bacterial DNA gyrase
5 fluorouracil
5-Fluorouracil
  • Antineoplastic
  • AntimetaboliteThymidylate synthase inhibitor
foscarnet
Foscarnet
  • Antiherpes
  • Pyrophosphate analogDirectly inhibits viral DNA polymerase
fulvestrant
Fulvestrant
  • AntineoplasticAntiestrogen
  • Estrogen receptor antagonist
ganciclovir
Ganciclovir
  • Antiherpes
  • Purine analogPhosphorylated to an inhibitorof viral DNA polymerase
gemtuzumab
Gemtuzumab
  • Antineoplastic
  • Anti-CD33 antibody
gentamicin
Gentamicin
  • Aminoglycoside antibioticbactericidal protein synthesis inhibitor
  • 30S ribosomeFreezes initiation
goserelin
Goserelin
  • AntineoplasticGonadotropin releasing hormone(GnRH) agonist
griseofulvin
Griseofulvin
  • Antifungal
  • Binds to microtubules
hydroxyurea
Hydroxyurea
  • Antineoplastic
  • MiscellaneousRibonucleotide reductase inhibitor
ibritumomab
Ibritumomab
  • Antineoplastic
  • Anti-CD20 antibody
imatinib
Imatinib
  • Antineoplastic
  • MiscellaneousTyrosine kinase inhibitor
imipenem cilastatin
Imipenem/Cilastatin
  • New b lactam antibiotic
  • Cilastatin inhibits akidney dipeptidase that inactivates imipenem
indinavir
Indinavir
  • Antiretroviral
  • Protease inhibitor (PI)
interferon alpha
Interferon alpha
  • Antiviral for hepatitisAntineoplasticCytokine
  • Anti-angiogenesis
interleukin 2
Interleukin 2
  • Cytokine Antineoplastic
interleukin 11
Interleukin 11
  • Cytokine Antineoplastic (supporting agent)
iodoquinol
Iodoquinol
  • Antiparasitic
  • Treatment of protozoal infections
iressa
Iressa
  • Antineoplastic
  • MiscellaneousTyrosine kinase inhibitor
isoniazid
Isoniazid
  • Antibiotic
  • Inhibits biosynthesis of mycolic acids Major drug for tuberculosis
itraconazole
Itraconazole
  • Triazole antifungal
  • Inhibits synthesis of ergosterol by inhibiting lanosterol 14a demethylase
ivermectin
Ivermectin
  • Antihelminthic
  • Treatment of intestinaland tissue roundworms
ketoconazole
Ketoconazole
  • Imidazole antifungal
  • Inhibits synthesis of ergosterol by inhibiting lanosterol 14a demethylase
lamivudine
Lamivudine
  • Antiretroviral
  • Nucleoside reverse transcriptase inhibitor (NRTI)
letrozole
Letrozole
  • AntineoplasticAntiestrogen
  • Aromatase Inhibitor
leucovorin
Leucovorin
  • Antineoplastic (supporting agent)
  • Folic acid analogue(used in methotrexate rescue)
leuprolide
Leuprolide
  • AntineoplasticGonadotropin releasing hormone (GnRH) agonist
linezolid
Linezolid
  • Oxazolidinone antibioticProtein synthesis inhibitor
  • 50S ribosomal subunit
lomustine ccnu
Lomustine (CCNU)
  • Antineoplastic
  • Alkylating Agent
macrolides erythromycin azithromycin clarithromycin
Macrolideserythromycin, azithromycin, clarithromycin
  • AntibioticsBacteriostatic protein synthesis inhibitors
  • 50S ribosome
mebendazole
Mebendazole
  • Antihelminthic
  • Treatment of intestinal roundworms
mechlorethamine
Mechlorethamine
  • Antineoplastic
  • Alkylating Agent
mefloquine
Mefloquine
  • Antimalarial
  • Treatment and prophylaxis for chloroquine resistant Plasmodium
meglumine antimonate
Meglumine antimonate
  • Tropical antiparasitic
  • Organic antimonialTreatment of Leishmaniasis
melarsoprol
Melarsoprol
  • Tropical antiparasitic
  • Treatment of African Trypanosomiasis in CNS
melphalan
Melphalan
  • Antineoplastic
  • Alkylating Agent
6 mercaptopurine
6-Mercaptopurine
  • Antineoplastic
  • Antimetabolite(“pseudofeedback inhibition” of HGPRT and PRP – purine synthesis)
mesna
Mesna
  • Antineoplastic (supporting agent)
  • Prevent hemorrhagic cystitisdue to cyclophosphamide
methenamine
Methenamine
  • Urinary tract antiseptic
  • Decomposes to formaldehydein acidic environment
methicillin
Methicillin
  • Penicillin antibioticCell wall synthesis inhibitor
  • Pencillinase resistant penicillin Inhibits peptidoglycan cross-linking
methotrexate
Methotrexate
  • ImmunosuppressiveAntineoplastic
  • Folic acid antagonistDihydrofolate reductase inhibitor
metronidazole
Metronidazole
  • AntibioticAntiparasiticAntiulcer
  • AnaerobesReduction leads to intermediatesthat damage DNA
miconazole
Miconazole
  • Imidazole antifungal
  • Inhibits synthesis of ergosterol by inhibiting lanosterol 14a demethylase
minocycline
Minocycline
  • Tetracycline antibioticBacteriostatic protein synthesis inhibitor
  • 30S ribosomePrevents aminoacyl tRNA attachment
mitomycin c
Mitomycin C
  • Antineoplastic
  • Natural productAntibiotic
muromonab cd3
Muromonab-CD3
  • Immunosuppressive
  • Mouse monoclonal anti-CD3 antibody Organ transplant (anti-rejection)
mycophenolate
Mycophenolate
  • Immunosuppressive
  • Inhibits inosine monophosphate dehydrogenase activity
nafcillin
Nafcillin
  • Penicillin antibioticCell wall synthesis inhibitor
  • Penicillinase resistant penicillinInhibits peptidoglycan cross-linking
nalidixic acid
Nalidixic acid
  • Urinary tract antiseptic
  • QuinoloneInhibits bacterial DNA gyrase
neomycin
Neomycin
  • Aminoglycoside antibioticBactericidal protein synthesis inhibitor
  • 30S ribosomeFreezes initiationTopical
netilmicin
Netilmicin
  • Aminoglycoside antibioticBactericidal protein synthesis inhibitor
  • 30S ribosomeFreezes initiation
nevirapine
Nevirapine
  • Antiretroviral
  • Non-nucleoside reverse transcriptase inhibitor (NNRTI)
nifurtimox
Nifurtimox
  • Tropical antiparasitic
  • Treatment of South American Trypanosomiasis; Chagas disease
nitrofurantoin
Nitrofurantoin
  • Urinary tract antiseptic
  • Reduction leads to intermediates that damage DNA
norfloxacin
Norfloxacin
  • Fluoroquinolone antibioticDNA replication inhibitor
  • Inhibits bacterial DNA gyrase
nystatin
Nystatin
  • AntifungalPolyene antibiotic
  • Binds to ergosterol & alters permeabilityTopical
organic antimonials
Organic antimonials

sodium stibogluconatemeglumine antimonate

  • Tropical antiparasitic
  • Treatment of Leishmaniasis
oseltamivir
Oseltamivir
  • Antiviral
  • Inhibits neuraminidase anddecreases viral release Treatment of Influenza A & B
oxacillin
Oxacillin
  • Penicillin antibioticCell wall synthesis inhibitor
  • Pencillinase resistant penicillinInhibits peptidoglycan cross-linking
oxytetracycline
Oxytetracycline
  • Tetracycline antibioticBacteriostatic protein synthesis inhibitor
  • 30S ribosomePrevents aminoacyl tRNA attachment
paclitaxel
Paclitaxel
  • Antineoplastic
  • Natural productPlant alkaloid (taxane)
palivizumab
Palivizumab
  • Antiviral
  • Monoclonal antibody againstthe surface ofrespiratory syncytial virus
para aminosalicylic acid
Para-aminosalicylic acid
  • AntibioticNucleic acid andprotein synthesis inhibitor
  • Inhibits dihydropteroate synthetaseSecondary TB drug
paromomycin
Paromomycin
  • AntiparasiticAminoglycoside antibiotic
  • Treatment of protozoal infections
penciclovir
Penciclovir
  • Antiherpes
  • Purine analogPhosphorylated to inhibitor of viral DNA polymerase
penicillins
Penicillins
  • b lactam antibioticsCell wall synthesis inhibitors
  • Inhibit cross-linking of peptidoglycan
penicillin g
Penicillin G
  • Penicillin antibioticCell wall synthesis inhibitor
  • Acid labileInhibits peptidoglycan cross-linking
penicillin v
Penicillin V
  • Penicillin antibioticCell wall synthesis inhibitor
  • More acid resistant than Penicillin GInhibits peptidoglycan cross-linking
pentostatin
Pentostatin
  • Antineoplastic
  • MiscellaneousEnzyme inhibitor(blocks purine synthesis)
piperacillin
Piperacillin
  • Penicillin antibioticCell wall synthesis inhibitor
  • Anti-pseudomonal penicillinInhibits peptidoglycan cross-linking
polymyxin b
Polymyxin B
  • AntibioticDisrupts gram negative cell membrane
  • Binds phosphatidylethanolamineBactericidal
praziquantel
Praziquantel
  • Antihelminthic
  • Treatment of trematode (fluke) and cestode (tapeworm) infections
primaquine
Primaquine
  • Antimalarial
  • Eliminates hepatic forms of plasmodium
procaine penicillin g
Procaine Penicillin G
  • Penicillin antibioticCell wall synthesis inhibitor
  • Repository preparationInhibits peptidoglycan cross-linking
pyrantel pamoate
Pyrantel Pamoate
  • Antihelminthic
  • Treatment of intestinal roundworms
pyrazinamide
Pyrazinamide
  • Antibiotic
  • Major drug for tuberculosis
pyrimethamine
Pyrimethamine
  • AntimalarialProtein and nucleic acid synthesis inhibitor
  • Plasmodial dihydrofolate reductase inhibitor
ribavirin
Ribavirin
  • Antiviral
  • Primarily used as aerosol for respiratory syncytial virus
rifampin
Rifampin
  • AntibioticNucleic acid synthesis inhibitor
  • Inhibits DNA dependent RNA polymeraseMajor drug for TB
rimantadine
Rimantadine
  • Antiviral
  • Inhibits replicationat the stage of uncoating Treatment of Influenza A
ritonavir
Ritonavir
  • Antiretroviral
  • Protease inhibitor (PI)
rituxumab
Rituxumab
  • Antineoplastic
  • Anti-CD20 antibody
saquinavir
Saquinavir
  • Antiretroviral
  • Protease inhibitor (PI)
silver sulfadiazine
Silver sulfadiazine
  • Sulfonamide antibioticMicrobial nucleic acidand protein synthesis inhibitor
  • Inhibits dihydropteroate synthetaseTopical
sirolimus
Sirolimus

Rapamycin

  • Immunosuppressive
  • Binds FKBP, inhibits mTOR (mammalian kinase target of rapamycin) & cell cycle progression
sodium stibogluconate
Sodium stibogluconate
  • Tropical antiparasitic
  • Organic antimonial Treatment of Leishmaniasis
spectinomycin
Spectinomycin
  • AntibioticBacteriostatic protein synthesis inhibitor
  • 30S ribosome
streptomycin
Streptomycin
  • Aminoglycoside antibioticBactericidal protein synthesis inhibitor
  • 30S ribosomeFreezes initiation
sulfacetamide
Sulfacetamide
  • Sulfonamide antibioticMicrobial nucleic acidand protein synthesis inhibitor
  • Inhibits dihydropteroate synthetaseTopical
sulfadoxine
Sulfadoxine
  • Sulfonamide antibioticMicrobial nucleic acidand protein synthesis inhibitor
  • Dihydropteroate synthetase inhibitor
sulfamethoxazole
Sulfamethoxazole
  • Sulfonamide antibioticMicrobial nucleic acidand protein synthesis inhibitor
  • Inhibits dihydropteroate synthetase
sulfisoxazole
Sulfisoxazole
  • Sulfonamide antibioticNucleic acid andprotein synthesis inhibitor
  • Inhibits dihydropteroate synthetase
sulfonamides
Sulfonamides
  • AntibioticsNucleic acid andprotein synthesis inhibitors
  • Inhibit dihydropteroate synthetase
suramin
Suramin
  • Tropical antiparasitic
  • Treatment of African Trypanosomiasis
tacrolimus
Tacrolimus
  • ImmunosuppressiveAntineoplastic
  • Binds FKBP (FK506 binding protein)Inhibits calcineurin
tamoxifen
Tamoxifen
  • Antineoplastic Antiestrogen
  • Estrogen receptor anatagonist
terbinafine
Terbinafine
  • Allylamine antifungal
  • Inhibits ergosterol synthesis by inhibiting squalene epoxidase
tetracycline
Tetracycline
  • AntibioticBacteriostatic protein synthesis inhibitor Antiulcer
  • 30S ribosomePrevents aminoacyl tRNA attachment
thalidomide
Thalidomide
  • Antineoplastic
  • Anti-angiogenicAnti-TNFLeprosy (not antibiotic)
thiabendazole
Thiabendazole
  • Antihelminthic
  • Treatment of intestinal roundworms
6 thioguanine
6-Thioguanine
  • Antineoplastic
  • Antimetabolite (“pseudofeedback inhibition” of HGPRT and PRP – purine synthesis)
thiotepa
Thiotepa
  • Antineoplastic
  • Alkylating agent
ticarcillin
Ticarcillin
  • Penicillin antibioticCell wall synthesis inhibitor
  • Anti-pseudomonal penicillinInhibits peptidoglycan cross-linking
tobramycin
Tobramycin
  • Aminoglycoside antibioticBactericidal protein synthesis inhibitor
  • 30S ribosomeFreezes initiation
trastuzumab
Trastuzumab
  • Antineoplastic
  • Anti-HER2 antibody
trifluridine
Trifluridine
  • Antiherpes
  • Pyrimidine analogPhosphorylated to inhibitor of viral DNA polymerase
trimethoprim
Trimethoprim
  • AntibioticProtein and nucleic acidsynthesis inhibitor
  • Inhibits bacterial dihydrofolate reductase
trimetrexate
Trimetrexate
  • Antibiotic
  • Folic acid antagonist Treatment for Pneumocystis carinii
tumor necrosis factor
Tumor necrosis factor 
  • CytokineAntineoplastic
valacyclovir
Valacyclovir
  • Antiherpes
  • Purine analogPhosphorylated to inhibitor of viral DNA polymerase
valganciclovir
Valganciclovir
  • Antiherpes
  • Purine analogPhosphorylated to inhibitor of viral DNA polymerase
vancomycin
Vancomycin
  • AntibioticInhibits cell wall synthesis
  • Not a b lactam
vinblastine
Vinblastine
  • Antineoplastic
  • Vinca alkaloidNatural product
vincristine
Vincristine
  • Antineoplastic
  • Vinca alkaloidNatural product
voriconazole
Voriconazole
  • Triazole antifungal
  • Inhibits synthesis of ergosterol by inhibiting lanosterol 14a demethylase
zalcitabine
Zalcitabine
  • Antiretroviral
  • Nucleoside reverse transcriptase inhibitor (NRTI)Dideoxycytidine (ddC)
zanamivir
Zanamivir
  • Antiviral
  • Inhibits neuraminidaseand decreases viral release Treatment of Influenza A & B
zidovudine
Zidovudine

Azidothymidine (AZT)

  • Antiretroviral
  • Nucleoside reverse transcriptase inhibitor (NRTI)