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UpToDate’s Value Proposition

Relevant Content. World-renowned Authors. Easy to Use. UpToDate’s Value Proposition. UpToDate synthesizes the most recent medical information into evidence-based, practical recommendations clinicians trust to make the right point-of-care decisions. UpToDate Facts-at-a-Glance.

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UpToDate’s Value Proposition

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  1. RelevantContent World-renowned Authors Easy to Use UpToDate’s Value Proposition UpToDate synthesizes the most recent medical information into evidence-based, practical recommendations clinicians trust to make the right point-of-care decisions.

  2. UpToDate Facts-at-a-Glance • 9,000+ topics in 18 specialties • Additional 5,000+ unique drug entries • 700+ patient information topics • 4,800+ physician authors, editors and peer reviewers • 7,700+ graded recommendations • 450,000+ users in 149 countries

  3. Specialties Covered in UpToDate Infectious Diseases Nephrology and Hypertension Neurology Obstetrics, Gynecology and Women’s Health Oncology Pediatrics Psychiatry* Pulmonary, Critical Care and Sleep Medicine Rheumatology Surgery* *In development Adult and Pediatric Emergency Medicine Adult Primary Care and Internal Medicine Allergy and Immunology Cardiovascular Medicine Dermatology* Endocrinology and Diabetes Family Medicine Gastroenterology and Hepatology Geriatrics Hematology Hospital Medicine

  4. UpToDate Is Trusted Worldwide UpToDate has users in 149countries

  5. UpToDate’s Editorial Process • Authored and edited by leading physicians • World-renowned expertise • Hand-searching of 460+ journals • Three-tiered peer review process

  6. UpToDate’s Editorial Process Our authors collaborate withmultiple specialty editors tocreate or update the topic. New clinical studiesare released thatimpact care. The topic ispeer-reviewed. UpToDateEditorial Process Topic is available to clinicians worldwide via UpToDate. A gradingeditor reviewsthe gradedrecommendations. Final topic contentconsensus is reached.

  7. Graded Recommendations Grades denote strength of recommendation and quality of evidence • Strong recommendation = Grade 1 [ “We recommend” ] • Weak recommendation = Grade 2 [ “We suggest” ] • Evidence = Grade A, B or C [ High, moderate or low quality ]

  8. Graded Recommendations Hierarchy of Evidence High - Quality Low - Quality Meta-analyses of randomized trials of high methodological quality Randomized trials with methodological limitations Observational studies Unsystematic clinical observations

  9. Users SayUpToDate Improves Care 94% improves quality of care 89% changed management 81% changed diagnostic testing 0% 20% 40% 60% 80% 100% Source: UpToDate Subscriber Survey, 2010

  10. Medical ProfessionalsEndorse UpToDate Pam Wetzel, MD Chief Medical Information OfficerSwedish American Hospital, Rockford, IL UpToDate “changes the wayyou practice medicine — really.”

  11. Medical ProfessionalsEndorse UpToDate Marc Greenwald, MD Chief of MedicineSignature Healthcare-Brockton Hospital, Brockton, MA UpToDate “applicability to patients is in evidence every day.”

  12. Medical ProfessionalsEndorse UpToDate “UpToDate is …a new way of practicing medicine …for day-to-day practice there is no other product.” R.M. Valentijn, MDMDHAGA Hospital, the Hague, the Netherlands

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