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Module 3: Cases studies of CRA and MRA - PowerPoint PPT Presentation

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Module 3: Cases studies of CRA and MRA
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  1. UNIT 3: KEY STAGES IN THE PROCESS OF RISK ASSESSMENT Module 3: Cases studies of CRA and MRA Christine CEZARD* (Unit co-ordinator) Anabel VITAS** Kofi Aidoo*** * IUT A USTL Lille France ** University of Navarra Pamplona Spain ***Glasgow Caledonian University

  2. INTRODUCTION 2 situations need risk assessment for food : • Acute crisis • for prevention purposes • to decide if a risk is acceptable for the population or not

  3. RISK ASSESSMENT: during acute crisis • 2 cases : unknown risk, sanitary alert • Data needed : • about the product • about populations at risk • about the kind of risk • about the extension of the epidemic • information from the sanitary agencies

  4. RISK ASSESSMENT: during acute crisis CHEMICAL RISK ASSESSMENT • Example: dioxins • Steps:

  5. RISK ASSESSMENT for prevention • Assessing exposure to the contaminant : • searching for all routes of exposure to the chemical substance • assessing for specific populations • Defining NOAELs or LOAELS for : • acute, subchronic and chronic toxicities • mutagenicity • carcinogenicity • effects on reproduction : fertility, development, teratogenicity

  6. RISK ASSESSMENT for prevention MICROBIOLOGICAL RISK ASSESSMENT • Example: Salmonellosis by consumption of egg products • Steps:

  7. RISK ASSESSMENT for prevention Practical microbiological risk assessmentState purpose of risk assessment

  8. RISK ASSESSMENT for prevention Practical microbiological risk assessmentHazard identification

  9. RISK ASSESSMENT for prevention Practical microbiological risk assessmentHazard characterisation

  10. RISK ASSESSMENT for prevention Practical microbiological risk assessmentExposure assessment

  11. RISK ASSESSMENT for prevention Practical microbiological risk assessmentRisk characterization

  12. RISK ASSESSMENT for prevention Practical microbiological risk assessmentRecord risk assessment

  13. RISK ASSESSMENT for prevention Practical microbiological risk assessmentReview risk assessment