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Molecular Structure of RyR Ryanodine Receptor: Insights from Samsó et al. (2005)

In the study by Samsó et al. (2005), the RyR Ryanodine Receptor's molecular structure is elucidated, revealing a cylinder 10 Å long and 8 Å in diameter. With 4 negative charges and 13 M of charge, as well as 8 oxygens with charge -1/2, the receptor's complex architecture occupies 18% of its available volume, making it a very crowded environment. Key findings highlight the presence of aspartate residues and offer valuable insights into the receptor's function.

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Molecular Structure of RyR Ryanodine Receptor: Insights from Samsó et al. (2005)

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  1. Samsó et al., 2005 RyRRyanodine Receptor • 4 negative charges • Cylinder 10 Å long, 8 Å diameter • 13 M of charge! • 8 oxygenswith charge -1/2 • 18% of available volume • Very Crowded! Aspartate

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