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Synergies of Knowledge in Healthcare

Synergies of Knowledge in Healthcare. Oren Fuerst, Ph.D. April 2007. Oren Fuerst. Personal Background Radiation therapy example Advanced versus disruptive surgery devices Commonalities between Homeland security and clinical study in Africa Open Discussion. Add-On to the Radiation Market.

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Synergies of Knowledge in Healthcare

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  1. Synergies of Knowledge in Healthcare Oren Fuerst, Ph.D. April 2007

  2. Oren Fuerst • Personal Background • Radiation therapy example • Advanced versus disruptive surgery devices • Commonalities between Homeland security and clinical study in Africa • Open Discussion 2007 BioVance Medical

  3. 2007 BioVance Medical

  4. Add-On to the Radiation Market Bio Protect Video 2007 BioVance Medical

  5. Intuitive Surgical (Nasdaq: ISRG) • Market Capitalization: $4.5bn (4/2007) • Founded 1995, IPO 2000 • 2006 Revenue $380M (55% device; 15% services; 30% disposables) • >50% revenue growth rate in ‘06 • Gross Profit Margin 67% • 559 Units installed (155 in 2006) • >$200k of disposable per device in 2006 • >35% of prostate surgeries in the U.S. are using the device • Main revenue from prostate, small base in gynecology and bariatric surgery Da-Vinci: Advanced and Expensive 2007 BioVance Medical

  6. Current “Futuristic” System- Da-Vinci 2007 BioVance Medical

  7. 2007 BioVance Medical

  8. The Future of Laparoscopic Surgery? 2007 BioVance Medical

  9. 2007 BioVance Medical

  10. Need for Early Detection (Source: DARPA-ITO) Phase II Acute Illness Phase I Initial Symptoms Traditional Disease Detection Early Detection Gain of 2 days Effective Treatment Period (Linear) Anthrax Attack Non Communicable Victims Directly Exposed 105 Fatalities Without Early Detection Number Dead Fatalities With Early Detection t = 0 2007 BioVance Medical Time (days) Animal or Human Indicators

  11. Anthrax cases at WHC, October 2001 2007 BioVance Medical

  12. Hygiea Information Flow 2007 BioVance Medical

  13. Hygiea Data Collection 2007 BioVance Medical

  14. Hygiea Data Collection 2007 BioVance Medical

  15. Hygiea Data Analysis 2007 BioVance Medical

  16. Suspect Mapping 2007 BioVance Medical

  17. 2007 BioVance Medical

  18. 2007 BioVance Medical

  19. 2007 BioVance Medical

  20. Contact Information • Dr. Oren Fuerst • +1 646 536 9289 • oren@biovancemedical.com 2007 BioVance Medical

  21. Seasoned Management • Zeil Rosenberg, M.D. - co-CEO More than 20 years of experience in the public and private health sectors (including being a medical director and worldwide area leader in BD (NYSE: BDX). Managing Director of BioVance Medical • Oren Fuerst, Ph.D. - co-CEO More than 20 years in technology development and business advisory. Former faculty at Columbia Business school and Yale School of Management. Managing Director of BioVance Medical • Shosh Friedman - Regulatory affairs Former EVP Regulatory affairs of Given Imaging (NASDAQ: GIVN). World renowned expert on rapid development and regulatory affairs. Winner of the RAPS award. VP RA of BioVance Medical • Roni Shabat – R&D ManagerFounder of Top R&D, a leading provider of Medical Device engineering solutions. • Dr. Adrian Paz, M.D. – Co-InventorSerial entrepreneur and inventor (Bio-Protect; Endogun; UltraSurge). Chief of the urological laparoscopic services at Barzilai medical center, Ashkelon. • Shaul Shohat- co-InventorM.Sc in analytical chemistry, more than 15 years experience in development of medical devices (including in Bio-Rad). CEO of Bioprotect 2007 BioVance Medical

  22. Minimally invasive insertion of balloon before RT to protect rectal tissue 2007 BioVance Medical

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