html5-img
1 / 26

NASG for Relief Settings

NASG for Relief Settings. Consultation on Reproductive Health Technologies for Crises Settings PATH & Women's Commission for Refugee Women and Children May 13-14, 2008 Suellen Miller, CNM, PhD Associate PRofessor UCSF, Dept Ob/Gyn & Reproductive Sciences. Pneumatic AntiShock Garment . PASG.

nenet
Download Presentation

NASG for Relief Settings

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript

  1. NASG for Relief Settings Consultation on Reproductive Health Technologies for Crises Settings PATH & Women's Commission for Refugee Women and Children May 13-14, 2008 Suellen Miller, CNM, PhD Associate PRofessor UCSF, Dept Ob/Gyn & Reproductive Sciences

  2. Pneumatic AntiShock Garment

  3. PASG • Did not make statistically significant difference in mortality and morbidity for lower body trauma patients (all ages, all dxs.) in urban settings with trauma centers • Use of PASG for obstetrical hemorrhage: • ONLY 6 cases reported • NO comparative trials

  4. NASG • Light-weight, reusable • Lower body counter pressure • Decreases bleeding • Reverses shock • May contribute to decreased morbidity and mortality

  5. 3 way stretch neoprene (wet suit material) Industrial strength Velcro Foam pressure ball over uterus

  6. THERAPEUTIC EFFECTS OF ANTISHOCK GARMENT • Efficient, simple & safe circumferential counterpressure RESUSCITATION OF CENTRAL CIRCULATION • Results in translocation of up to 30% of total blood volume from lower body to core REDUCES HEMORRHAGE IN LOWER BODY • Decrease in arterial perfusion pressure to the uterus, comparable to ligation of the internal iliac arteries. • Overcomes pressure in capillary and venous system (15-25 mm Hg.), reduction of transmural pressure, vessel radius and flow.

  7. USES • Stabilizes patient while evaluating, transporting, or preparing for definitive surgical treatment. • Can be safely and comfortably used up to 48 hours. • May arrest bleeding and avoid surgical intervention. • May decrease need for or number of blood transfusions • During delays, such as waiting for interventional radiology

  8. Obstetric Hemorrhage NASG

  9. What NASG Does NOT DO Does not avert the necessity for evaluation • to identify cause of shock • to manage fluid and blood replacement • to provide appropriate therapy for coagulopathy

  10. Little Experience with NASG • 206: Egypt (results published) • Results being analyzed • 540: Egypt II • 580: Nigeria • 1126 women treated with the NASG to date

  11. Egypt: 364 Women • 50% lower median measured blood loss in the drape, 68% decrease in morbidity and mortality

  12. Median Pulse Recovery Times from Kaplan-Meier Survival Analysis * Log Rank Test adjusted for pulse at admission = 21.20, p=0.000

  13. Findings Promising • Clinically promising: faster recovery, shorter time of oxygen deprivation, lower blood loss THAN standard treatment • Statistically significant on PROXY indicators • OUTCOMES OF INTEREST: Mortality and Morbidity, not statistically significant • Lower quality design, PRE/POST

  14. Lack of Evidence for Crisis Settings • To date, these results have all been obtained at tertiary care facilities with access to surgery, blood and sufficient supplies, anesthesiologists, etc. • Currently testing whether application at a clinic prior to transfer will affect outcomes

  15. Applicability for Relief Settings • Easy to use • Training for application, management and removal just a few hours • Can stabilize patients for transport to a referral facility

  16. Barriers to Use in Relief Settings • Institutional capacity(tested in tertiary centers) • NASG is first aid - not definitive treatment • Facilities must be able to provide • Oxygen • Normal Saline • Blood • Uterotonics and other medicines • Surgery/anesthesia • NASG buys time, but patients still need to be monitored, so adequate staffing, essential drugs and equipment are important • Provider training and retraining is required, new staff must constantly be trained

  17. Barriers cont. • Referral protocols • Referral hospitals that will receive referred patients must first be trained and proficient • Patients need to be sent to the correct facility • If referral protocol is not correctly implemented, the patient’s greatest risk is improper removal of the NASG by untrained staff • Protocols for garment cleaning and return or exchange need to be established

  18. Barriers cont. • Community acceptance • Patient compliance varies by site • Patient education for life-threatening situations is difficult and problematic

  19. Barriers cont. • Care and maintenance • Highly correlated with the lifespan of the NASG • Adequate supply of clean water required • Not difficult, but must be done properly; not intuitive, needs training, re-training and support • Cleaning staff need to be trained to properly clean, fold, and store • Time lost due to clean ones not available • Time lost due to improper folding

  20. NIH/GATES Collaboration: UCSF, WHO/RHR, CREP, UTH, UZ • Randomized Cluster Trial • Zambia and Zimbabwe • Standard Treatment (uterotonics/IVs) and Application of NASG at midwifery-led peripheral clinics or Standard Treatment • Transport to Tertiary Care Hospital where all women receive NASG • Sample size large enough to demonstrate 50% decrease in M&M

  21. Brees C, Hensleigh PA, Miller S, Pelligra R. (2004). A non-inflatable anti shock garment for obstetric hemorrhage. Int J Gynaecol Obstet, 87 (2), 119-124, 2004. • *Miller, S, Hamza, S, Bray E, Gipson R, Nada, K, Fathalla, M, Mourad, M. et al. First Aid for Obstetrical Hemorrhage: The Pilot Study of the Non-pneumatic Anti-Shock Garment (NASG) in Egypt. British Journal of Obstet Gynaecol, 113(4): p. 424-9, 2006. • Miller, S., Turan, JM, Ojengbede A, Ojengbede, O, Fathalla, M, Morhason-Bello, IO, Mourad, M, Galandanci, H, Hamza, S, Awaal, M, Akinwuntan, A, Mohammed AI, McDonough, L, Dau, K, Butrick, E, and Hensleigh, P. The Pilot Study of the Non-pneumatic Anti-Shock Garment (NASG) in Women with Severe Obstetric Hemorrhage: Combined Results from Egypt and Nigeria. Int J Gynaecol Obstet, 94(S3), ps43-s44. 2006 • * Miller, S & Hensleigh, P. Non-pneumatic Anti-shock Garment for Obstetric Hemorrhage.Book Chapter, in International Federation of Obstetrics and Gynecology (FIGO) Book, Postpartum Hemorrhage: New Thoughts, New Approaches, Editors: C. B-lynch, A. LaLonde, L. West,. Sapiens Publications, UK. 2006 • * Miller, S, Ojengbede A, Turan J, Ojengbede O, Butrick E, Hensleigh, P. Anti-Shock Garments for Obstetric Hemorrhage. Current Women’s Health Reviews, 3(1), 3-11, 2006. • * Miller, S, Turan, JM, Dau, K, Fathalla M, Mourad M, Sutherland, T, Hamza, S. et al. Decreasing Maternal Mortality from Hypovolemic Shock in Low Resource Settings: the Non-pneumatic Anti-Shock Garment (NASG). Global Public Health Journal, 2(2);110-24, 2006.

  22. Thank you….. • Questions???

More Related