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Dr. Nina Lewis, Consultant Gastroenterologist, provides insights on investigating dysphagia, weight loss, anemia, and diarrhea for suspected upper GI cancer. Referral processing details and diagnostic testing recommendations are also included.
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Suspected Upper GI cancer 2WW pathway: direct access pilot Dr Nina Lewis Consultant Gastroenterologist and Honorary Assistant Professor
What I think • Dysphagia needs oesophageal cancer and lung cancer excluding. In appropriate patients, dysphagia lends itself to be investigated in a direct-to-test way
What I think • Dysphagia needs oesophageal cancer and lung cancer excluding. In appropriate patients, dysphagia lends itself to be investigated in a direct-to-test way. • Patients presenting with any weight loss, iron def anaemia or diarrhoea need to be assessed in an outpatient clinic so that tests appropriate for the individual patient are organised
What I think • Dysphagia needs oesophageal cancer and lung cancer excluding. In appropriate patients, dysphagia lends itself to be investigated in a direct-to-test way • Patients presenting with any weight loss, iron def anaemia or diarrhoea need to be assessed in an outpatient clinic so that tests appropriate for the individual patient are organised • Many patients do not fit into typical symptomology for a specific cancer but please continue to follow your instinct and refer
Processing of Upper GI 2WW referrals Cancer Office deliver paper copies of upper GI 2WW referrals in a marked folder to Front Desk, City Hospital Endoscopy Nina Lewis or Lorraine Clark vet referrals daily by 13:00 Straight to test OGD Gastroenterology clinic
Processing of Upper GI 2WW referrals Cancer Office deliver paper copies of upper GI 2WW referrals in a marked folder to Front Desk, City Hospital Endoscopy Nina Lewis or Lorraine Clark vet referrals daily by 13:00 Straight to test OGD Gastroenterology clinic • Dysphagia • Dyspepsia (that seems straightforward)
Oesophageal cancer Most common presenting symptom is dysphagia
Oesophageal cancer Dysphagia is caused by the malignant stricturing
Chronic peptic ulcer disease Helicobacter accounts for: • 85% duodenal ulcers • 60% gastric ulcers NSAIDs account for: • 14% duodenal ulcers • 30% gastric ulcers
Gastro-oesophageal reflux • Absence of oesophagitis at endoscopy does not exclude reflux (may require pH studies) • Common exposures: - young men - abdominal truncal obesity - hiatus hernia - delayed gastric emptying
Processing of Upper GI 2WW referrals Cancer Office deliver paper copies of upper GI 2WW referrals in a marked folder to Front Desk, City Hospital Endoscopy Nina Lewis or Lorraine Clark vet referrals daily by 13:00 Straight to test OGD Gastroenterology clinic • Iron def anaemia • Weight loss • Diarrhoea • Palpable mass • Anyone you are worried about
Upper GI 2WW outpatient assessment for iron def anaemia • Test to confirm or refute she has bowel cancer • Test to confirm or refute she has UGI cancer • Look for other site of malignancy particularly if weight loss is present • Imaging +/- cystoscopy to confirm or refute she has urological cancer if haematuria present • Small bowel biopsy to exclude coeliac disease • Gastric biopsy to exclude helicobacter-associated gastritis whilst on aspirin
Iron def anaemia and bowel cancer ~50% people with incident bowel cancer have evidence of IDA
Upper GI 2WW outpatient assessment for iron def anaemia • Test to confirm or refute she has bowel cancer • Test to confirm or refute she has UGI cancer • Look for other site of malignancy particularly if weight loss is present • Imaging +/- cystoscopy to confirm or refute she has urological cancer if haematuria present • Small bowel biopsy to exclude coeliac disease • Gastric biopsy to exclude helicobacter-associated gastritis whilst on aspirin
Gastric cancer • Often asymptomatic • Presence of weight loss, post-prandial vomiting, iron def anaemia all reflect advanced disease
Processing of Upper GI 2WW referrals Cancer Office deliver paper copies of upper GI 2WW referrals in a marked folder to Front Desk, City Hospital Endoscopy Nina Lewis or Lorraine Clark vet referrals daily by 13:00 Straight to test OGD Gastroenterology clinic • Iron def anaemia • Weight loss • Diarrhoea • Palpable mass • Anyone you are worried about • Dysphagia • Dyspepsia (that seems straightforward)
Pilot: GP direct access to Upper GI 2WW OGD or 2WW clinic GP direct access following 2WW UGI referral Straight to test OGD Gastroenterology clinic • Iron def anaemia • Weight loss • Diarrhoea • Palpable mass • Anyone you are worried about • Dysphagia • Dyspepsia (that seems straightforward)