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RAP. Retinal angiomatous proliferation. Edi Ladavac. General Hospital Pula. AMD. Drusen. Atrophic type. Exudative form. Exudative AMD. CNV Disciform scar Choroidal-retinal anastomosis. Exudative AMD = CNV. ? ? ?. Exudative AMD. Yannuzzi (2001)
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RAP Retinal angiomatous proliferation Edi Ladavac General Hospital Pula
AMD Drusen Atrophic type Exudative form
Exudative AMD CNV Disciform scar Choroidal-retinal anastomosis
Exudative AMD = CNV ? ? ?
Exudative AMD Yannuzzi (2001) • choroidal neovascularisation(CNV) • retinal angiomatous proliferation (RAP) • polypoidal choroidal neovascularisation NEW !
RAP • White patients • bilateral • Dg. FAG + ICGA + OCT • therapy
RAP – clinical picture Stage I - IRN (intraretinal neovascularisation) Stage II - SRN (subretinal neovascularisation) Stage III - CNV (choriodal neovascularisation)
RAP – stage I • Intraretinal angiomatous proliferation • RRA (retinal-retinal anastomosis) • Hemorrhages
RAP – stage II • retinal elevation • reaction of the RPEa • PED
RAP stage III • Choroidal neovascularisation (CNV) • Retinal-choroidal anastomosis (RCA)
RAP- diagnosis • Biomicroscopic examination • FAG • ICGA • OCT
RAP – case report • Small hemorrhages Case II Case I
RAP –case report • Feeding arteriole (dilated vessels) Case II Case I
RAP - case report • Retinal oedema • PED Case II Case I
RAP – case report • ICG angiography Case II Case I Trieste – Padova 2004
RAP - therapy • PDT + triamcinolone intravitreal • VEGF inhibitors (Macugen) intravitreal • Macular surgery • Laser
RAP - therapy • Triamcinolone + PDT Before th After th OCT OCT Trieste - 2004
RAP - conclusion CNV AMDRAP PCN Exudative form