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Antimicrobial resistance surveillance in Ireland. Results of invasive enterococcal bacteraemia surveillance, 2009 **** Data as of 01/12/2010 ****. Ireland is a member of the European Antimicrobial Resistance Surveillance Network (EARS-Net).

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Antimicrobial resistance surveillance in ireland

Antimicrobial resistance surveillance in Ireland

Results of invasive enterococcal bacteraemia surveillance, 2009

**** Data as of 01/12/2010 ****

Ireland is a member of the European Antimicrobial Resistance Surveillance Network (EARS-Net)


Ears net enterococci objective and case definition
EARS-Net Enterococci:Objective and case definition

Objective:

  • To determine the proportions of enterococci, E. faecalis or E. faecium, isolates from blood that are resistant to 3 key antibiotic classes:

    • Ampicillin

    • High-level gentamicin

    • Vancomycin

      Case definition:

  • EARS-Net collects data on the first invasive isolate (from blood only) of E. faecium per patient per quarter


Caveats in interpreting ears net data
Caveats in interpreting EARS-Net data

  • Care must be exercised when interpreting the raw figures, i.e. increases in numbers of isolates, as the numbers of laboratories reporting to EARS-Net has increased over the years

  • EARS-Net data does not distinguish clinically significant isolates from contaminants

  • If a resistant isolate is identified subsequent to a susceptible one within the same quarter, then that isolate is not counted (and similarly if susceptible isolates is identified subsequent to resistant one)


Antimicrobial resistance surveillance in ireland

For further information on antimicrobial resistance and EARS-Net in Ireland, including quarterly and annual reports, plus reference/ resource material on the individual pathogens under surveillance, see:

http://www.hpsc.ie/hpsc/A-Z/MicrobiologyAntimicrobialResistance/EuropeanAntimicrobialResistanceSurveillanceSystemEARSS/


Antibiotic codes and abbreviations
Antibiotic codes and abbreviations: EARS-Net in Ireland, including quarterly and annual reports, plus reference/ resource material on the individual pathogens

AMP, Ampicillin HLG, High-Level Gentamicin

LNZ, Linezolid QDA, Quinupristin-Dalfopristin

TEC, Teicoplanin VAN, Vancomycin

AMR, Antimicrobial Resistance

MDR, Multi-Drug Resistance

EFA, Enterococcus faecalis

EFM, Enterococcus faecium

VREfm, Vancomycin-Resistant E. faecium

VSEfm, Vancomycin-Susceptible E. faecium

MDR, Multi-Drug Resistance


Enterococcus faecalis
Enterococcus faecalis EARS-Net in Ireland, including quarterly and annual reports, plus reference/ resource material on the individual pathogens


Numbers and resistance proportions of e faecalis from bacteraemia 2002 2009
Numbers and resistance proportions of EARS-Net in Ireland, including quarterly and annual reports, plus reference/ resource material on the individual pathogens E. faecalis from bacteraemia, 2002-2009

* Not all isolates tested


E faecalis bacteraemia resistance trends 2002 2009
E. faecalis EARS-Net in Ireland, including quarterly and annual reports, plus reference/ resource material on the individual pathogens bacteraemia resistance trends, 2002-2009

Number of laboratories participating by year-end and quarter are indicated above the bars


Numbers and proportions of e faecalis bacteraemia by hospital type 2009
Numbers and proportions of EARS-Net in Ireland, including quarterly and annual reports, plus reference/ resource material on the individual pathogens E. faecalis bacteraemia by hospital type, 2009


Susceptibility data for e faecalis bacteraemia isolates 2009 n 389
Susceptibility data for EARS-Net in Ireland, including quarterly and annual reports, plus reference/ resource material on the individual pathogens E. faecalis bacteraemia isolates, 2009 (n=389)


Resistance profiles of e faecalis isolates in 2009
Resistance profiles of EARS-Net in Ireland, including quarterly and annual reports, plus reference/ resource material on the individual pathogens E. faecalis isolates in 2009


Age and sex distribution of patients with invasive e faecalis infection in 2009
Age and sex distribution of patients with invasive EARS-Net in Ireland, including quarterly and annual reports, plus reference/ resource material on the individual pathogens E. faecalis infection in 2009


Age and sex specific incidence rates of e faecalis bacteraemia in 2009
Age and sex-specific incidence rates of EARS-Net in Ireland, including quarterly and annual reports, plus reference/ resource material on the individual pathogens E. faecalis bacteraemia in 2009

ASIR, Age-Specific Incidence Rate (per 100,000 population)


Mean median mode and range of ages of patients with e faecalis bacteraemia in 2009
Mean, median, mode and range of ages of patients with EARS-Net in Ireland, including quarterly and annual reports, plus reference/ resource material on the individual pathogens E. faecalis bacteraemia in 2009


Sex distribution of patients with e faecalis bacteraemia in 2009
Sex distribution of patients with EARS-Net in Ireland, including quarterly and annual reports, plus reference/ resource material on the individual pathogens E. faecalis bacteraemia in 2009

In patients with laboratory-confirmed invasive E. faecalis infection in 2009, males were approximately 1.6-times more likely to get an infection than females (highly significant, P<0.0001).


E faecalis distribution of high level gentamicin resistance in earss ears net countries 2009
E. faecalis EARS-Net in Ireland, including quarterly and annual reports, plus reference/ resource material on the individual pathogens - distribution of high-level gentamicin resistance in EARSS/EARS-Net countries, 2009

Map downloaded from:

http://ecdc.europa.eu/en/activities/surveillance/EARS-Net/Pages/Database.aspx on 21/12/2010


E faecalis distribution of high level gentamicin resistance in earss countries 2008
E. faecalis EARS-Net in Ireland, including quarterly and annual reports, plus reference/ resource material on the individual pathogens - distribution of high-level gentamicin resistance in EARSS countries, 2008

Map downloaded from http://www.rivm.nl/earss/database/ on 24/08/2009


E faecalis distribution of vancomycin resistance in earss ears net countries 2009
E. faecalis EARS-Net in Ireland, including quarterly and annual reports, plus reference/ resource material on the individual pathogens - distribution of vancomycin resistance in EARSS/EARS-Net countries, 2009

Map downloaded from:

http://ecdc.europa.eu/en/activities/surveillance/EARS-Net/Pages/Database.aspx on 21/12/2010


E faecalis distribution of vancomycin resistance in earss countries 2008
E. faecalis EARS-Net in Ireland, including quarterly and annual reports, plus reference/ resource material on the individual pathogens - distribution of vancomycin resistance in EARSS countries, 2008

Map downloaded from http://www.rivm.nl/earss/database/ on 24/08/2009


Enterococcus faecium
Enterococcus faecium EARS-Net in Ireland, including quarterly and annual reports, plus reference/ resource material on the individual pathogens


Numbers and resistance proportions of e faecium from bacteraemia 2002 2009
Numbers and resistance proportions of EARS-Net in Ireland, including quarterly and annual reports, plus reference/ resource material on the individual pathogens E. faecium from bacteraemia, 2002-2009

* Not all isolates tested


E faecium bacteraemia resistance trends 2002 2009
E. faecium EARS-Net in Ireland, including quarterly and annual reports, plus reference/ resource material on the individual pathogens bacteraemia resistance trends, 2002-2009

Number of laboratories participating by year-end and quarter are indicated above the bars


Invasive mdr e faecium trends 2002 2009
Invasive MDR EARS-Net in Ireland, including quarterly and annual reports, plus reference/ resource material on the individual pathogens E. faecium trends, 2002-2009

Number of laboratories participating by year-end and quarter are indicated above the bars



Numbers and proportions of mdr e faecium bacteraemia by hospital type 2009
Numbers and proportions of MDR type, 2009E. faecium bacteraemia by hospital type, 2009


Susceptibility data for e faecium bacteraemia isolates 2009 n 397
Susceptibility data for type, 2009E. faecium bacteraemia isolates, 2009 (n=397)


Resistance profiles of e faecium isolates in 2009
Resistance profiles of type, 2009E. faecium isolates in 2009


Trends in numbers of main resistance profiles of e faecium isolates 2002 2009
Trends in NUMBERS of main resistance profiles of type, 2009E. faecium isolates, 2002-2009

Number of laboratories participating by year-end and quarter are indicated above the bars


Trends in proportions of main resistance profiles of e faecium isolates 2002 2009
Trends in PROPORTIONS of main resistance profiles of type, 2009E. faecium isolates, 2002-2009


Age and sex distribution of patients with invasive e faecium infection in 2009
Age and sex distribution of patients with invasive type, 2009E. faecium infection in 2009


Age and sex specific incidence rates of e faecium bacteraemia in 2009
Age and sex-specific incidence rates of type, 2009E. faecium bacteraemia in 2009

ASIR, Age-Specific Incidence Rate (per 100,000 population)


Mean median mode and range of ages of patients with e faecium bacteraemia in 2009
Mean, median, mode and range of ages of patients with type, 2009E. faecium bacteraemia in 2009


Sex distribution of patients with e faecium bacteraemia in 2009
Sex distribution of patients with type, 2009E. faecium bacteraemia in 2009

In patients with laboratory-confirmed invasive E. faecium infection in 2009, males were approximately 1.3-times more likely to get an infection than females (significant, P=0.005).


E faecium distribution of high level gentamicin resistance in earss ears net countries 2009
E. faecium type, 2009 - distribution of high-level gentamicin resistance in EARSS/EARS-Net countries, 2009

Map downloaded from:

http://ecdc.europa.eu/en/activities/surveillance/EARS-Net/Pages/Database.aspx on 21/12/2010


E faecium distribution of high level gentamicin resistance in earss countries 2008
E. faecium type, 2009 - distribution of high-level gentamicin resistance in EARSS countries, 2008

Map downloaded from http://www.rivm.nl/earss/database/ on 24/08/2009


E faecium distribution of vancomycin resistance in earss ears net countries 2009
E. faecium type, 2009- distribution of vancomycin resistance in EARSS/EARS-Net countries, 2009

Map downloaded from:

http://ecdc.europa.eu/en/activities/surveillance/EARS-Net/Pages/Database.aspx on 21/12/2010


E faecium distribution of vancomycin resistance in earss countries 2008
E. faecium type, 2009- distribution of vancomycin resistance in EARSS countries, 2008

Map downloaded from http://www.rivm.nl/earss/database/ on 24/08/2009