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ODONTOGENIC TUMOURS

ODONTOGENIC TUMOURS. Odontogenic tumors. Are related to the jaws since they originate from the tissues associated with tooth development. A) Benign tumors:- Epithelial origin:- Ameloblastoma Calcifying epithelial odonogenic tumor Squamous odontogenic tumor

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ODONTOGENIC TUMOURS

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  1. ODONTOGENIC TUMOURS

  2. Odontogenic tumors Are related to the jaws since they originate from the tissues associated with tooth development.

  3. A) Benign tumors:- Epithelial origin:- Ameloblastoma Calcifying epithelial odonogenic tumor Squamous odontogenic tumor Clear cell odontogenic tumor Mesenchymal origin:- Odontogenic fibroma Odontogenic myxoma Benign cementoblastoma ODONTOGENIC TUMOURS

  4. Mixed epithelial and mesenchymal origin:- • Calcifying odontogenic cyst • Ameloblastic fibroma • Adenomatoidodontogenic tumors • Odontoma (complex or compound) • Ameloblastic fibro-odontoma • Tumor of odontoameloblastoma

  5. B) Malignant tumors:- 1. Epithelial origin: • Malignant ameloblastoma • Primary intraosseous Carcinoma • Carcinoma from odontogenic cyst 2. Ecto-mesenchymal origin:- • Ameloblasticfibrosarcoma • Ameloblasticfibroodontosarcoma

  6. Benign tumorsEpithelial origin • Ameloblastoma • Calcifying epithelial odont. tumor • Squamous odontogenic tumor • Clear cell odontogenic tumor

  7. Ameloblastoma • Is a slowly growing locally invasive benign tumor. • It hasthree types: 1- Conventional solid or multicystic 2- Unicystic ameloblastoma 3- Peripheral ameloblastoma

  8. Ameloblastoma • Mostly seen in mandible (80%) • (70%) in molars & ascending ramus • It is symptomless & swelling may appear at later

  9. The origin of ameloblastoma is either from: 1. Epithelial rest of enamel organ 2. Developmental enamel organ 3. Epithelial lining of odontogenic cyst 4. Basal cells of oral mucosa

  10. Histopathological Types a- Follicular type b- Plexiform ameloblastoma c- Basal cell ameloblastoma d- Granular ameloblastoma e- Desmoplastic ameloblastoma f- Acanthomatous ameloblastoma

  11. c) Squamous odontogenic tumor • arises from the epithelial rest of Malassiz within the periodontal ligament on the lateral surface of the root of vital tooth. • It may be painful or painless associated with tooth mobility or it may be asymptomatic & discovered by radiograph.

  12. Radiograph:- • A trianglular radiolucent area lateral to root of tooth. • Histopathology:- • Circumscribed round or more irregular islands of squamous epithelium within flattened peripheral cells set in fibrous stroma, may contain lamellae, calcified lobular eosinophilic material. • Treatment:- • occasionally invade the surrounded tissue, however, in maxilla may invade the antrum, curettage & extraction of tooth is effective

  13. d) Clear cell odontogenic tumor • It is a very rare intraosseous tumor, most cases reported in female (over 50 years of age). It may be difficult to distinguish it from primary or metastatic clear cell tumors. It behaves as locally aggressive tumor with high rate of recurrence.

  14. Radiograph:- • Unilocular or multilocular radiolucency with well defined margin. • Histopathology:- • Poorly circumscribed tumor composed of sheet of cells with clear cytoplasm rich in glycogen lying in a fibrous stroma. • Differential diagnosis of clear cell odontogenic tumor:- • 1- intraosseousmucoepidermoid CA (clear cell variant) • 2- Calcifying epithelial odontogenictumor

  15. Calcifying Epithelial Odontogenic Tumor (PindBorg tumor)

  16. It is a rare tumor occurs at about 40 years of age (at posterior body of mandible). Asymptomatic slowly growing tumor. • It originates from epithelial rest of dental lamina and/or reduced enamel epithelium. • It could be central mainly occurs at molar area or peripheral mainly occurs at anterior part of the mouth as superficial soft tissue swelling of gingiva.

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