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Chapter 35 Medication Administration

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Chapter 35 Medication Administration. To safely and accurately administer medications you need knowledge related to: Pharmacology Pharmacokinetics Life sciences Human anatomy Mathematics. Scientific Knowledge Base. Federal regulations State and local regulation of medication

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Presentation Transcript
scientific knowledge base

To safely and accurately administer medications you need knowledge related to:

    • Pharmacology
    • Pharmacokinetics
    • Life sciences
    • Human anatomy
    • Mathematics
Scientific Knowledge Base
medication legislation and standards

Federal regulations

  • State and local regulation of medication
  • Health care institutions and medication laws
  • Medication regulations and nursing practice
Medication Legislation and Standards
pharmacological concepts

Drug names:

    • Chemical, generic, trade
  • Classification
  • Medication forms:
    • Solid, liquid, other oral forms, topical, parenteral, instillation into body cavities
Pharmacological Concepts

The study of how medications:

    • Enter the body
    • Are absorbed and distributed into cells, tissues, or organs
    • Alter physiological functions

The passage of medication molecules into the blood from the site of administration

  • Factors that influence absorption:
    • Route of administration
    • Ability to dissolve
    • Blood flow to site of administration
    • Body surface area
    • Lipid solubility of medication

After absorption, distribution occurs within the body to tissues, organs, and to specific sites of action.

  • Distribution depends on:
    • Circulation
    • Membrane permeability
    • Protein binding

Medications are metabolized into a less potent or an inactive form.

  • Biotransformation occurs under the influence of enzymes that detoxify, degrade, and remove active chemicals.
  • Most biotransformation occurs in the liver.

Medications are excreted through:

    • Kidney
    • Liver
    • Bowel
    • Lungs
    • Exocrine glands
medication interactions

Occur when one medication modifies the action of another

  • A synergistic effect occurs when the combined effect of two medications is greater than the effect of the medications given separately.
Medication Interactions
nursing knowledge base

Safe administration is imperative.

  • Nursing process provides a framework for medication administration.
  • Clinical calculations must be handled without error.
    • Conversions in and between systems
    • Dose calculations
    • Pediatric and elderly calculations
Nursing Knowledge Base
prescriber s role

Prescriber can be physician, nurse practitioner, or physician’s assistant.

  • Prescribers must document the diagnosis, condition, or need for each medication.
  • Orders can be written, verbal, or by telephone.
Prescriber’s Role
medication administration

Pharmacist’s role

  • Distribution system
  • Nurse’s role
  • Medication error
Medication Administration
nursing process and medication administration


  • Diagnosis
  • Planning
  • Implementation
  • Evaluation
Nursing Process and Medication Administration
medication administration21


  • Topical
  • Inhalation
  • Irrigation
  • Parenteral
  • Injections
Medication Administration