Ceramic Biomaterials (Bioceramics)
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Ceramic Biomaterials (Bioceramics). The class of ceramics used for repair and replacement of diseased and damaged parts of the musculoskeletal system are referred to as bioceramics . OBJECTIVES to examine chemical/physical properties of ceramics
Ceramic Biomaterials (Bioceramics)
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Ceramic Biomaterials (Bioceramics) • The class of ceramics used for repair and replacement of diseased and damaged parts of the musculoskeletal system are referred to as bioceramics. • OBJECTIVES • to examine chemical/physical properties of ceramics • to introduce the use of ceramics as biomaterials
Ceramics • (keramikos- pottery in Greek) • Ceramics are refractory polycrystalline compounds • Usually inorganic • Highly inert • Hard and brittle • High compressive strength • Generally good electric and thermal insulators • Good aesthetic appearance
Structure • Ceramic Structure: AmXn ZnS A: metal, +ve CsCl NaCl X: nonmetal, -ve
Types of Ceramics nearly bioinert
Inert Ceramics: Aluminum Oxides (Alumina) • Applications • orthopaedics: • femoral head • bone screws and plates • porous coatings for femoral stems • porous spacers (specifically in revision surgery) • knee prosthesis • dental: crowns and bridges
Alumina • Inertness: • advantage is that it makes material more biocompatible • disadvantage: • nonadherent fibrous membrane at the interface. • interfacial failure can occur, leading to implant loosening
Inert Ceramics: Zirconia, ZrO2 • zirconium; named from the Arabic, zargun = gold color • Fabrication: • Obtained from the mineral zircon • Addition of MgO, CaO, CeO, or Y2O3 stabilize tetragonal crystal structure (e.g. 97 mol%ZrO2 and 3 mol%Y2O3) • Usually hot-pressed or hot isostatically pressed • Applications: • orthopaedics: femoral head, artificial knee, bone screws and plates, favored over UHMWPE due to superior wear resistance • dental: crowns and bridges
Biodegradable Ceramics: Calcium Phosphates • Almost all bioresorbable ceramics are variations of calcium phosphate • Uses • repair material for bone damaged trauma or disease • void filling after resection of bone tumours • repair and fusion of vertebrae • repair of herniated disks • repair of maxillofacial and dental defects • ocular implants • drug-delivery
Biodegradable Ceramics: Calcium Phosphate • Structure resembles bone mineral; thus used for bone replacement • Coating of metal implants to promote bone ingrowth • Different forms exist depending on Ca/P ratio, presence of water, impurities and temperature
Bioactive Ceramics: Glass Ceramics • Bioactive: capable of direct chemical bonding with the host biological tissue • Glass: • an inorganic melt cooled to solid form without crystallization • an amorphous solid • possesses short range atomic order BRITTLE! • Glass-ceramic is a polycrystalline solid prepared by controlled crystallization of glass LESS BRITTLE
SiO2 B C A D CaO Na2O Bioactive Ceramics: Glass ceramics A: Bonding within 30 days B: Nonbonding, reactivity too low C: Nonbonding, reactivity too high D: Bonding
Mechanical Properties CHEE 340