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Objective for. System of Quality of. Measure Life. Team Members. Maja Middleton – Team Leader Kayla Ericson – Communicator Kristin Riching – BSAC Katherine Davis - BWIG. Client Dr. Erwin B. Montgomery M.D. Department of Neurology Advisor Prof. Justin Williams BME Department.

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team members
Team Members

Maja Middleton – Team Leader

Kayla Ericson – Communicator

Kristin Riching – BSAC

Katherine Davis - BWIG


Dr. Erwin B. Montgomery M.D.

Department of Neurology


Prof. Justin Williams

BME Department

problem statement
Problem Statement
  • Design a system or tool to measure the quality of life for a patient suffering from movement disorders.
  • The system/device must provide evidence that the quality of life has improved post surgery so that insurance companies will continue to fund deep-brain stimulus rehabilitation.
quality of life
Quality of Life
  • Definition: Quality of life is a measure of the means that people live within their own environments in ways that are best for them
  • Applicable Definition: The ultimate goal of deep brain stimulation surgery is to enable people to live quality lives -- lives that are both meaningful and enjoyed, but are also functional mentally, physically and socially.
three aspects of quality of life
Three Aspects of Quality of Life
  • Mental – Patient’s feelings and attitudes about themselves and their abilities as related to their disease and quality of life
    • Cognitive assessment (PADLS or MSQOL54)
  • Physical – Patient’s ability to perform daily tasks
    • Bluetooth accelerometer
  • Social – Patient’s daily interactions with society and personal relationships
    • GPS
  • All three aspects will be measured pre- and post-surgery
background material and research
Background Material and Research

Movement Disorder Symptoms


Postural Instability


Bradykinesia / akinesia


Absence of movement


Abnormal, involuntary movement

Side effect of drug therapy

previous methods
Previous Methods
  • No previous devices for objective measure of movement disorders found besides written questionnaires and doctor judgment.
  • Doctor observation is becoming less accepted as insurance companies lean toward evidence based medicine
background material and research1
Background Material and Research
  • Insurance companies only pay for necessary rehabilitation treatments that bring the patient to a normal functioning level for their environment
    • They continue to fund treatments so long as progress continues
    • All progress is marked on a scale that relates to daily functions of life
      • Reaching, lifting, standing, walking, dressing, etc…
deep brain stimulation
Deep Brain Stimulation
  • For neurologically based movement disorders
  • Two electrodes implanted in the brain are fed to a pulse generator implanted in the chest
  • The generator delivers high-frequency electrical stimulation that shuts down nerve cells to allow cells to regain self-control

Figure 1: http://www.clevelandclinic.org/neuroscience/techniques/dbs.htm

physical design specifications
Physical Design Specifications
  • Accelerometers
    • 5 subunits
      • One for each wrist (2 total)
      • One for each ankle (2 total)
      • One on the trunk as a reference
    • Bluetooth enabled
      • Allows for wireless messaging of data to

the central PDA

Depth: 5mm

35 mm

35 mm

Figure 2: Top picture - front view; bottom picture – back view


physical technical aspects
Physical Technical Aspects
  • All accelerometers need to communicate together – done via the PDA and Bluetooth technology
  • Each signal must be recognized individually by the PDA (X, Y, Z data in ASCII format – number for a character)
  • Will sample at 20 Hz (Nyquis’ Theorem)
  • Battery life (Lithium ion) is about 60 hours (840 mAh – 3.7V)
  • Has A-D conversion
central integration unit
Central Integration Unit
  • Hewlett Packard - Personal Desktop Assistant (PDA)
    • Bluetooth enabled PDA
    • CompactFlash slot
    • Expansion slot in PDA for memory capabilities
    • USB port for easy PC interfacing

HP iPAQ2215

Figure 3: http://www.circuitcity.com/detail.jsp?c=1&b=g&u=c&qp=0&bookmark=bookmark_0&oid=74016&catoid=-8028&m=0

central unit technical aspects
Central Unit Technical Aspects
  • PDA
    • 64 MB internal RAM
    • Up to 512 MB of add-on memory
    • 900 mAh lithium rechargeable battery
    • Software must be programmed for PDA to record and store GPS data (every half hour)
    • Software must also be programmed to receive, store, and manipulate accelerometer data
    • All programming will be done using the software development kit (SDK) from Microsoft
social design specifications
Social Design Specifications
  • Laipac Global Positioning System (GPS)
    • Tracking GPS compact flash card (to log distance and location)
    • Low power consumption
    • Windows compatible

Figure 4: http://www.laipac.com/gps_tf30cf_eng.htm

social technical aspects
Social Technical Aspects
  • GPS
    • Record readings every half hour
    • Accurate to 25 m
    • 3.3 V
    • .2 W power consumption
    • PDA driver is downloadable from the website
thank you
Thank you!
  • We just want to extend our thanks to:
      • Dr. Montgomery
      • Prof. Justin Williams
      • Dr. Jim Abbs
      • Daryn Belden
      • Gary Diny, PT
future work
Future Work
  • The plan for the device is thoroughly mapped out. The next steps include:
    • Purchasing the PDA and CompactFlash card
    • Writing the software with the SDK for the GPS
    • Purchasing the pieces for the accelerometer
    • Purchasing the circuit board and assembling the system
    • Design and build casing for the accelerometers
    • Write software using the SDK for the accelerometer
    • Test the integrated system
overall schematic
Overall schematic

Reference Accelerometer

Integrated PDA and GPS

Upload data to PC


Figure 5: www.circuitcity.com

  • Davis, William R. Personal Interview. 14 Feb. 2004.
  • Department of Neurology. (2001). What are Movement Disorders and How are they Treated? Retrieved March 8, 2004, from Baylor College of Medicine Web site: http://www.bcm.tmc.edu/neurol/struct/park/park6.html
  • Diny, Gary. Personal Interview. 27 Feb. 2004.
  • Hobson, J.P., et al., eds. “The Parkinson’s Disease Activities of Daily Living Scale: a new simple and brief subjective measure of disability in Parkinson’s disease.” Clinical Rehabilitation 15:1 (2001): 241-246.
  • Meyers, Allan R., et al., eds. “Health-Related Quality of Life in Neurology.” Neurology and Public Health 57:1 (2000): 1224-1227.
  • Montgomery, Erwin B. Personal Interview. 27 Jan. 2004.
  • Deep Brain Stimulation surgery. Retrieved April 25, 2004. http://www.clevelandclinic.org/neuroscience/techniques/dbs.htm
  • Deep Brain Stimulation Surgery. Retrieved April 25, 2004. www.wemove.org