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Learn about mortality rates, surgical and medical management options, and outcomes of aortic dissection repair. Understand the complexities, techniques, and long-term follow-up of this critical condition.
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Surgery for Aortic Dissection Adrian E. Manapat, M.D.
Mortality of Aortic Dissection Acute aortic dissection Lindsay, Hurst (1967) : 33% within 24 hrs 50% within 48 hrs 80% within 7 days 95% within 1 month for Type B 25% at 1 month Acute/Chronic/A/B Anagnostopoulos (1972) 70% at 1 week 90% at 3 months
Management of acute aortic dissection Type A dissection Surgical repair (Modes of exit: Cardiac tamponade MI Heart failure from AI Stroke) Type B dissection Medical > Surgical Risk of cardiac tamponade 2%
Management of Type B dissection Indications for surgery 1. Life threatening complications of dissection a) Aortic rupture/leak b) Infarction/ischemia of major end organ (kidneys, abdominal viscera, extremities) 2) Progression of dissection during medical treatment Indications for medical management 1) Elderly 2) Coexisting serious medical problem - cardiac, pulmonary, renal , peripheral or cerebrovascular 3) Thrombosed false lumen 4) Primary tear in distal aorta or abdominal aorta Craig Miller, 1992
Principles of repair • Complete obliteration of the tear of the ascending aorta • Obliteration of the false lumen • Prevention of rupture of the jeopardized segment • Correction of aortic regurgitation if present
What is so difficult about repair of aortic dissection? • Weakened friable aorta does not tolerate clamping - requires “no touch technique” • Need for deep hypothermic circulatory arrest Prolonged complex operation Almost all of them bleed Potential for multiple organ damage Possible catastrophic complications • Emergency nature
Deep hypothermic circulatory arrest (DHCA) • Every 10 o decrease in T causes a 50% decrease in metabolic rate - protects the organs from the effects of circulatory arrest • Safe period CA is usually 45 minutes • Disadvantages: prolonged surgery bleeding potential for end organ damage
Cerebral protection during circulatory arrest Cerebral perfusion • Antegrade perfusion via carotid arteries • Retrograde perfusion via superior vena cava Adjunctive measures: • Head packed in ice • Mannitol, steroids • Sodium pentothal • Trendelenberg position
Surgical options • Supracoronary AA replacement • Bentall procedure (composite ascending aorta & aortic valve replacement w/ re-implantation of coronary ostia) • Supracoronary AA replacemnt w/ aortic valve repair or replacement • Any of the above combined with CABG
Dealing with the aortic valve Resuspension of the commissures to repair the aortic valve Insertion of a valved conduit
Results of Surgical repair Operative (30-day) mortality 1960’s 30-60% 1990’s to the present 5-30% Cleveland Clinic experience (208) predictors of mortality:Earlier operative year Hypotension Non-use of DHCA Composite valve graft CABG Late survival (Crawford, 1990) 1 year 78% Acute type A 5 yrs 56% 5 years 63% 10 yrs 46% 10 years 55% 20 yrs 30%
Long term follow up • Lifelong antihypertensive, B blocker • Anticoagulation for prosthetic valve • Surveillance : new dissections aneurysm formation prosthetic valve function