Welcome!. Moderator: James R. Swearengen, DVM, DACLAM, DACVPM Senior Director, AAALAC International. The Peer Review Process: What Happens After the Exit Briefing? Kathryn Bayne, MS, PhD, DVM, DACLAM, CAAB, Senior Director and Director of Pacific Rim Activities, AAALAC International
Moderator: James R. Swearengen, DVM, DACLAM, DACVPM Senior Director, AAALAC International
Kathryn Bayne, MS, PhD, DVM, DACLAM, CAAB
Senior Director and Director of Pacific Rim Activities
i.e., there is peer review of the peer review…
Dale G. Martin, DVM, PhD, DACLAM, DACVPM,
DECLAM, Senior Director, Laboratory Animal Science
and Welfare, sanofi-aventis
AAALAC may say in a Suggestion for Improvement (SFI): Many of the rodents were housed on wire-bottom cages for both short and long term studies. While wire-bottom caging may enhance sanitation, there is evidence that suggests rodents prefer bedded solid-bottom cages. In addition, pressure neuropathy may result when animals are housed on wire-bottom cages for extended periods of time. The IACUC should review the use of wire-bottom caging for rodents and ensure that caging enhances animal well-being consistent with good sanitation and the requirements of each research project.The structural environment for rodents did not include items that increase the opportunity for expression of species-typical postures and activities and enhance the animals’ well being. These behavioral management needs should be reviewed to conform with recommendations of the Guide.
AAALAC may say in a Suggestion for Improvement (SFI): Hand washing of animal runs and cages can provide effective sanitation but requires attention to detail. Uniform procedures and practices should be implemented for ensuring consistent sanitation of animal cages and equipment. It is particularly important to ensure that surfaces are rinsed free or residual chemicals and that personnel have appropriate equipment to protect themselves from exposure to hot water or chemical agents used in the process. If hand washing is used, monitoring should be instituted to ensure effective sanitation.
AAALAC may say in a Suggestion for Improvement (SFI): Although the dog runs were flushed twice a day with water, they were only cleaned with detergent once per year. Consequently, many runs had algae growth on the concrete. The runs should be cleaned and disinfected regularly. The timing of pen or run cleaning should take into account normal behavioral and physiological processes of the animals.Mineral deposits were present on many of the cages in Rooms X,Y,Z>. Minerals and organic compounds in the urine from animals often adhere to cage surfaces and necessitate treatment with acid solutions before washing. Cage washing practices should be improved to minimize animal waste accumulations and provide proper sanitation.
Dennis M. Stark, DVM, PhD, DACLAM
Executive Director, Veterinary Sciences,
Pharmaceutical Research Institute, Bristol-Myers Squibb
James J. Elliott, DVM, DACLAM
Director, Department of Laboratory Animal ResourcesUniversity of Texas Health Science Center at San Antonio