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Explore the dynamics and components involved in cell migration at a glance. Learn about key proteins and their roles in the migration process, from leading edge to trailing edge.
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Cell Migration at a Glance Miguel Vicente-Manzanares, Donna J. Webb, Alan Rick Horwitz Click on indicated areas for expanded views Click here for node map Trailing edge Leading edge
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APC, Adenomatous poliposis coli; CAS, p130CAS (Crk-associated substrate) Crk, CT10 regulator of kinase; Eb1, end binding protein-1; Ena/VASP, Enabled/ Vasodilator activated phosphoprotein ERK, extracellular-regulated kinase FAK, focal adhesion kinase GIT, G protein coupled receptor interacting protein LIMK, LIM kinase mDia, mouse Diaphanous MHC, myosin heavy chain MLC, myosin light chain MRCK, myotonic dystrophy kinase-related Cdc42 binding kinase; PAK, p21-activated kinase Par, partition-defective proteins PKC, protein kinase C WASP, Wiskott-Aldrich syndrome protein WAVE/Scar, WASP-verprolin homolog/ Suppressor of cAMP receptor BACK Abbreviations