Economic Analysis In Clinical Research. Martin L. Brown, Ph.D. Applied Research Program Division of Cancer Control and Population Sciences National Cancer Institute email@example.com. Introduction to the Principles and Practice of Clinical Research October 31, 2005. Overview. Introduction
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Martin L. Brown, Ph.D.
Applied Research Program
Division of Cancer Control and Population Sciences
National Cancer Institute
Introduction to the Principles and
Practice of Clinical Research
October 31, 2005
ICER = [Eb – Ea] / [Cb – Ca]
Note: This is the equation for the slope of a line when E is the vertical axis and C is the horizontal axis
Source: H. Varmus, Disease Specific Estimates of Direct and Indirect Costs of Illness and NIH Support
Brown ML, et al. Medical Care 2002 Aug;40(8 Suppl):104-17.
Source: Yabroff et al. Medical Care, 2005.
Source: PS Romano, et al. Folic acid fortification of grain: an economic analysis. AJPH 1995:85:667-676.
Source: Kelly AE, et al. Appendix B in Gold, et al. Cost-Effectiveness
in Health and Medicine. Oxford U. Press, 1996.
Source: Williams et al. Teratology 2002;66:33-39; Waitzman , personal comm.
Source: D. Howard, et al. Institute of Medicine, 2005.
Gain of 114 life years
Costs increase by $12 million
Cost per life year gained of increasing inventory from 150,000 to 200,000 units is $105,000 = $12,000,000 114
Source: Neymark et al, Health Economics 2002;11:233-248.
Source: Goldie et al. NEJM 2005, in press. Treatment of Prostate Cancer