Coronary CT Angiography. Intern 柳復威. Udo Hoffmann, Maros Ferencik, Ricardo C. Cury, and Antonio J. Pena Coronary CT Angiography J Nucl Med May 1 2006 47: 797-806.
Image quality improved at low heart rates (<65 beats per minute)
1. the inspirational breath hold (-6beats/min)
2. oral ß-blocker (50—100mg oral or 5–20 mg i.v.
3. combination (-11beats/min)
4. short-acting nitroglycerin (selective coronary angiography )
determination of the adequate initiation of the coronary CTA image acquisition to ensure homogeneous contrast enhancement of the entire coronary artery tree
1. the timing bolus technique
2. the bolus tracking technique
The minimal equipment requirement for state-of-the-art coronary CTA is a 16-slice scanner. However, 40- or 64-slice MDCT scanners are recommended, as they increasethe volume coverage and permit reduction of the scan time and the amount of contrast agent.
(ECG-controlled dose modulation is 7–11mSv)
For the confirmation of pathologic findings in the long and short axes of the vessel.
enhance the visualization of coronary artery stenosis in a long-axis view of the vessel if narrowing is caused by noncalcified atherosclerotic plaque
moderate sensitivity (about 80%) and excellent specificity (about 90%)
1. detects calcified or mixed plaque with sensitivities and specificities above 90%.
2. the detection of noncalcified plaques, with sensitivities and specificities ranging from 60% to 85%, but has the potential to further stratify noncalcified plaque into fibrous plaque and lipid-rich plaque
3. smaller plaques (＜0.5 mm) are not detected
Other potential applications