1 / 14

Collaborative Addiction Research in Asian Populations Home and Abroad

Collaborative Addiction Research in Asian Populations Home and Abroad. International Conference on Global Health: Prevention and Treatment of Substance Use Disorders and HIV Taipei, Taiwan April 18, 2013. Gavin Bart, MD PhD FACP FASAM Director, Division of Addiction Medicine

mendel
Download Presentation

Collaborative Addiction Research in Asian Populations Home and Abroad

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript

  1. Collaborative Addiction Research in Asian Populations Home and Abroad International Conference on Global Health: Prevention and Treatment of Substance Use Disorders and HIV Taipei, Taiwan April 18, 2013 Gavin Bart, MD PhD FACP FASAM Director, Division of Addiction Medicine Department of Medicine Hennepin County Medical Center Associate Professor of Medicine University of Minnesota bartx005@umn.edu

  2. Hmong and opiate dependence • Validate the assessment tool • MINI versus SSADDA • Prevalence • Laos ~ 10% • Thailand ~15% • US ~3% • Mode • Smoking opium • Smoking heroin Malison 2011; Westermeyer 1981, 1995; Wiewel 2005

  3. Hmong entering treatment Westermeyer and Chitasombat 1996

  4. Methadone maintained Hmong: psychiatric comorbidity Bart 2013

  5. Hmong treatment outcome • Behavioral only ~90% relapse • Methadone ~80% retention • Hmong 49.0 mg (17.4) • Non-Hmong 77.1 mg (25.1) Bart 2012

  6. Hmong: a pocket of people Listman et al, 2007 and unpublished data

  7. Hmong genotype v. phenotype Straka et al. 2006

  8. R-methadone population pharmacokinetics:Hmong and non-Hmong Bart 2013

  9. More questions • Why are the Hmong different? • Diet • Transporter function • Genetics • Can we predict methadone dose requirements? • Does this happen with other medications?

  10. Why Research? • To find cures to disease and illness • Describe the situation • Epidemiology • Cohort studies • Compare approaches • Outcome • Quality of life / Satisfaction • Cost-effective • To inform policy

  11. Research resources

  12. Thank You • NIDA K23 DA024663 • SAMHSA • PEPFAR • USAID • CDC • Vietnam VAAC • FHI360 • Yih-IngHser • Betty Tai • NIDA R13DA035084

More Related