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This study explores the effectiveness of K14-Cre-ER in targeting intestinal epithelial stem cells, shedding light on its potential implications for regenerative medicine and disease modeling. The findings are detailed in the study by G. Mascré et al. published in Nature, highlighting the intricate processes involved in stem cell targeting and modulation using genetic tools.
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K14-Cre-ER targets IFE SCs. G Mascré et al. Nature000, 1-6 (2012) doi:10.1038/nature11393