Jane Goodwin BSc, MSc Nurse Practitioner. Drugs and the Eye. A&P. A & P. Pharmacology. A solution is a liquid vehicle for drug delivery to the eye. Solutions have a shorter contact time. Drops drain into lacrimal apparatus, into the nose and are absorbed systemically.
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Drugs and the Eye
EG – 0.5% Chloramphenicol = 500mg of Chloramphenicol in 100ml of solution.
Edge of lens
Occlude Inner Canthus
E.g. atropine, tropicamide and cyclopentolate
E.g. adrenaline and phenylephine
IS SIGHT THREATENING!
Is a sudden rise in intra ocular pressure. This is caused by an acute blockage in the drainage system – stopping the aqueous humour drain from the eye. Symptoms include a red painful eye, reduced vision, nausea, headache and can be in one or both eyes.
= problem with aqueous drainage
Micro-organisms can gain access as a result of:-
Types of conjunctivitis
Herpes – Dendritic Ulcer
Corneal Ulcer, with pus in AC
Corneal Foreign Body
Under surface of eye lid (sub tarsal plate)
Overdose or prolonged use can exaggerate some of the normal physiological actions of corticosteroids leading to mineralocorticoid and glucocorticoid side effects
Systemic steroids have a high risk (75%) of inducing a cataract
Retinal damage & Keratopathy
Ethambutol is included in a Rx regime when there is resistance to other TB drugs
The dark patches show loss of vision
Causes visual disturbances including corneal changes, cataracts and Retinopathy
Dead Corneal epithelium
3 Layers of Tear Film