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Skrivnostni svet nekodirajočih delov evkariontskih genomov Kordiš Dušan

Skrivnostni svet nekodirajočih delov evkariontskih genomov Kordiš Dušan Odsek za biokemijo in molekularno biologijo, IJS, Ljubljana. Nekodirajoča DNA zavzema pretežni del genomov pri eukariontih. Genomska arhitektura. Chromosome organization. Evolucija kromosomov.

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Skrivnostni svet nekodirajočih delov evkariontskih genomov Kordiš Dušan

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  1. Skrivnostni svet nekodirajočih delov evkariontskih genomov Kordiš Dušan Odsek za biokemijo in molekularno biologijo, IJS, Ljubljana

  2. Nekodirajoča DNA zavzema pretežni del genomov pri eukariontih

  3. Genomska arhitektura

  4. Chromosome organization

  5. Evolucija kromosomov

  6. The forces affecting genome size evolution

  7. Velikosti genomov in število genov pri prokariontih in eukariontih

  8. Funkcionalna evolucija nekodirajoče DNA

  9. Deletion of a conserved noncoding sequence selectively reduces expression of cytokine genes over a long distance

  10. Percent identity plots comparing human and other sequences at three loci(CNS:red, exons:blue, introns:yellow)

  11. Cis-regulatorna evolucija gradual, stepwise accumulation of sites that impart quantitatively greater Hox influence over gene regulation

  12. Important regulatory inventions leading to the crown group bilaterians

  13. Cis-regulatory logic during development

  14. Introni: izvor, evolucija in vloga v genomu

  15. Transpozicijski elementi

  16. B. McClintock: odkritje transpozicijskih elementov/dinamični genom

  17. Kakšen % genoma zavzemajo TE

  18. Spremembe sesalskih genomov po retrotranspoziciji L1 elementov

  19. Kakšen vpliv ima načina razmnoževanja na preživetje TE nespolno spolno

  20. Povezava ekologije in velikosti genoma: dinamika genoma na populacijskem nivoju

  21. Kako lahko Alu elementi poškodujejo človeški genom ? Homologna rekombinacija med Alu elementi

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