Data Provenance Workshop. Natalia Maltsev MCS Argonne National Laboratory. 98 published genomes 652 on-going genomes. So much data!!. Hmmm …. Why Biotechnological Revolution?. High-throughput technologies provide huge amounts of biological data: Sequence data
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Argonne National Laboratory
652 on-going genomes
Hmmm…Why Biotechnological Revolution?
Structure & Function
Pathways & Physiology
Biology in a Nutshell(for people with little knowledge but infinite intelligence)
Seq1 – function alcohol dehydrogenase
Seq2_Homo_sapiens GSGITKGLGAGANPEVGRNS AEEDRDALRAALDGSDMVFIAAGMGGGTGTGAAPVVAE
F1 with probability P1
F2 with probability P2
How reliably can we
predict this pathway?
What approach will
Increase our confidence