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Lecture 4 Genes and Their Functions ( 2 )

Lecture 4 Genes and Their Functions ( 2 ). In the previous lecture. Heredity materials Nucleic acids and their structures Mutations and gene functions DNA replication DNA recombination Mutation mechanisms. Main contents included in Chapter 8 and GO of Part II in our textbook.

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Lecture 4 Genes and Their Functions ( 2 )

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  1. Lecture 4Genes and Their Functions (2)

  2. In the previous lecture • Heredity materials • Nucleic acids and their structures • Mutations and gene functions • DNA replication • DNA recombination • Mutation mechanisms

  3. Main contentsincluded in Chapter 8 and GO of Part II in our textbook.

  4. 1. Gene Expression processes

  5. The Flow of Genetic Information from DNA via RNA to Protein

  6. QuestionWhat is Open reading frames, ORF?

  7. What is process of gene transcript? Question

  8. What is concept for alternative splicing in gene transcript? Question

  9. Are there any other kinds of gene products except proteins? Question

  10. Different RNAs • Ribosomal RNAs (rRNAs): translation • Transfer RNAs (tRNAs): translation • Messenger RNAs (mRNAs): protein template • Noncoding RNAs(ncRNAs): various types and functions

  11. Noncoding RNAs (ncRNAs) in eukaryotes Small RNA (sRNA) in bacteria Small nuclear RNAs (snRNAs) Small nucleolar RNAs (snoRNAs) MicroRNA(miRNA) Small temporal RNAs(stRNAs) Small interfering RNAs(siRNAs) RNA interference (RNAi) Guide RNAs(gRNAs) tRNA/mRNA: tmRNA

  12. How does the mRNA translate? Question

  13. What is the post-translation processes of proteins? Question

  14. Protein Subcellular Localization

  15. Folding Modification Transportation Active proteins

  16. How does a virus replicate its genome in a host cell? Question

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