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This study explores how the covalent conjugation and non-covalent binding of Ubiquitin work synergistically to stabilize the 2CARD tetramer structure. The research findings, published in Nature (2014), shed light on the molecular mechanisms underlying this stabilization process.
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Covalent conjugation and non-covalent binding of Ub synergize to stabilize the 2CARD tetramer. A Peisleyet al. Nature 000, 1-7 (2014) doi:10.1038/nature13140