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Metabolism of Protein

Metabolism of Protein. Amino Acids. Protein Structure:. Made up of a combination of about 20 naturally occurring amino acids Joined by Peptide Bonds Carboxyllic acid and an amino group. Role of the Liver:. Amino Acids stored in liver, blood stream and body tissues

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Metabolism of Protein

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  1. Metabolism of Protein Amino Acids

  2. Protein Structure: • Made up of a combination of about 20 naturally occurring amino acids • Joined by Peptide Bonds • Carboxyllic acid and an amino group

  3. Role of the Liver: • Amino Acids stored in liver, blood stream and body tissues • Amino Acids can be transferred from one of these locations to another • Amino acids are stored by deamination so that they can be used as an energy source (ATP)

  4. Amino Acids as a Fuel Source • Amino acids are only used as a fuel source during starvation • When there is an abundance of amino acids they are converted into glucose (gluconeogenesis) and fatty acids and glycerol (lipogenesis)

  5. Waste Products of Protein Metabolism • Deaminationforms ammonia which is toxic • The liver detoxifies ammonia by converting it into the less toxic, water soluble substance urea.

  6. Hormones and Protein Metabolism • Human growth hormone and insulin increase the uptake of amino acids and protein synthesis in muscle tissue. • Thyroid hormones also regulate protein metabolism • Androgens from the testes and the adrenal gland stimulate protein synthesis.

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