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Pt should abstain from using this prescription drugs for anesthesia for 7 days prior to surgery. An exception to this rule is for patients who have received a coronary stent and are receiving aspirin as a part of dual antiplatelet therapy.<br>
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Aspirin (Ecotrin) Well known drug to cause bronchoconstriction / bronchospasm. Be especially conscious of this in patients with reactive airways.
Pt should abstain from using these prescription drugs for anesthesia for 7 days prior to surgery. An exception to this rule is for patients who have received a coronary stent and are receiving aspirin as a part of dual antiplatelet therapy. Unless absolutely contraindicated, these patients should continue taking aspirin throughout the perioperative period. If absolutely contraindicated patient should stop aspirin 3 days prior to surgery. ALWAYS consult with a cardiologist before discontinuing dual antiplatelet therapy.
Prolongs bleeding time by causing platelet dysfunction that lasts the platelet’s entire life span (8-9 days). The effects are irreversible.
Platelet infusion will be necessary in cases where platelet function has been severely compromised by aspirin.
Toxic doses of aspirin stimulate the respiratory center of the brain leading to hyperpnea (hyperventilation), hypocapnea, and respiratory acidosis. Other toxic effects include hypoglycemia, metabolic acidosis, fluid/electrolyte losses, and hypermetabolism.
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