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Learn about the challenges in diagnosing ovarian cancer early and the leading symptoms and influencing factors. Explore current screening methods and preventative measures, along with advancements in early detection.
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Troubles in Diagnosing Ovarian Cancer Early English 12 Ryan Booker Taylor Davis Paul Han Joshua Boatright
Statistics and Average Diagnosis • As stated by O’Rourke and Mahon “ Ovarian Cancer is the leading cause of gynecologic cancer and the fifth leading cause of cancer deaths among American Women.” (2002) • White women have the highest incidence and death rate from ovarian cancer
Statistics and Average Diagnosis Cont. • Ovarian Cancer is the leading cause of death in industrialized nations
Leading Symptoms • Abdominal bloating and discomfort • Dyspepsia • Changes in bowel or bladder function • Constipation • Inability to urinate • Weight loss or gain
Aspects That Influence Onset • Age • Hereditary • Fertility/Infertility • Environmental Conditions • Obesity • HRT (Hormonal Replacement Therapy)
Cancerous Ovary Healthy Ovary
Oral Contraceptives Pregnancy Breast Feeding Salpingo-Oophorectomy Preventative Measures
Current Applications and Screening • Physical Examination • CA-125 • Ultrasound
Advancements in Early Detection • Blood Tests • Lysophosphatidic Acid (LPA) • Epidermal Growth Factor (p110ErbB1) • Osteopontin • Ovarian Pap Test • Laparoscopy
Work Cited • About Ovarian Cancer. [Internet]; c 1999-2002 [Updated 200 Jan. 28; cited 2006 Jan. 31]: Available from: http://images.google.com/imgres?imgurl=http://www.domain-b.com/companies/companies_d/dr_reddys_labs/ovarian_cancer%2520copy.jpg&imgrefurl=http://www.domain-b.com/companies/companies_d/dr_reddys_labs/20000128ovarian_cancer.html&h=200&w=250&sz=9&tbnid=xtgcCKLQxNW_1M:&tbnh=84&tbnw=106&hl=en&start=14&prev=/images%3Fq%3DOvarian%2BCancer%26svnum%3D10%26hl%3Den%26lr%3D%26sa%3DN • Anderiesz C, Quinn MA. Cancer Screening: Screening for Ovarian Cancer. Med. Journal of Austarlia [Internet]. 2003. [cited 2005 Jan 31]; 178 (12): 655-656. Available from: http://images.google.com/imgres?imgurl=http://www.mja.com.au/public/issues/178_12_160603/and10666_fm-2.jpg&imgrefurl=http://www.mja.com.au/public/issues/178_12_160603/and10666_fm.html&h=537&w=580&sz=44&tbnid=789YO8Rg_NCMRM:&tbnh=122&tbnw=132&hl=en&start=27&prev=/images%3Fq%3DOvarian%2BCancer%26start%3D20%26svnum%3D10%26hl%3Den%26lr%3D%26sa%3DN • Bilateral Salpingo-Oopherectomy with Perforation of the Colon-Medical Illustration. [internet]. Kennesaw, GA: Nucleus Medical Art inc; c1999-2006. [cited 2006 Jan. 31] Available from: http://images.google.com/imgres?imgurl=http://catalog.nucleusinc.com/imagescooked/10175W.jpg&imgrefurl=http://catalog.nucleusinc.com/generateexhibit.php%3FID%3D10175%26ExhibitKeywordsRaw%3D%26TL%3D32737%26A%3D2&h=291&w=432&sz=35&tbnid=NWBRvhrQlbHpvM:&tbnh=82&tbnw=123&hl=en&start=1&prev=/images%3Fq%3DSalpingo-Oophorectomy%26svnum%3D10%26hl%3Den%26lr%3D%26sa%3DG • Image Details (of the Female Ovaries) [Internet]. NetterImages.com: The Most Trusted Name In Medical Illustration. [Cited 2005 Jan 31] Available from: http://www.netterimages.com/images/vpv/000/000/005/5094-0550x0350.jpg • Leiomyoma and Ovarian Cancer. [internet]. [cited 2006 Jan. 31]. Available from:http://images.google.com/imgres?imgurl=http://www.gynoncology.com/common_files/Ovarian%2520Cancer%2520and%2520Leiomyoma%2520200.jpg&imgrefurl=http://www.gynoncology.com/common_files/Leiomyoma%2520and%2520Ovarian%2520Cancer.htm&h=152&w=200&sz=10&tbnid=_tRvVGr0blaWIM:&tbnh=75&tbnw=99&hl=en&start=5&prev=/images%3Fq%3DOvarian%2BCancer%26svnum%3D10%26hl%3Den%26lr%3D%26sa%3DN • O’Rourke J. Mahon SM. A Comprehensive Look at the Early Detection of Ovarian Cancer. Clinical Journal of Oncology Nursing [internet]. 2003 [updated 2003 Jan/Feb; cited 2006 Jan. 26]: 7(1): 1-7. Available from: http://search.epnet.com/login.aspx?direct=true&db=hch&an=9377306 • Stevens LM, Lynm C. JAMA. Patient Page: Ovarian Cancer. JAMA: Journals American Medical Association. [internet]. 2002. [cited 2005 Jan. 31]: 288:406. Available from: http://images.google.com/imgres?imgurl=http://www.medem.com/medem/images/jamaarchives/JAMA_Cancer_Ovarian_lev20_OvarianCancer_JPP_01.gif&imgrefurl=http://www.medem.com/medlb/article_detaillb.cfm%3Farticle_ID%3DZZZ45WOOO3D%26sub_cat%3D164&h=454&w=450&sz=52&tbnid=RdUE65CdwFwS_M:&tbnh=124&tbnw=122&hl=en&start=45&prev=/images%3Fq%3DOvarian%26start%3D40%26svnum%3D10%26hl%3Den%26lr%3D%26sa%3DN • The Risk of Ovarian Cancer. (ROCA). Study. [intnet]. National Cancer Institute (US); [cited 2006 Jan. 31]. Available from: http://images.google.com/imgres?imgurl=http://epi.grants.cancer.gov/ovarian/images/Group4.gif&imgrefurl=http://epi.grants.cancer.gov/ovarian/&h=148&w=200&sz=5&tbnid=NT7OjoZorpDQSM:&tbnh=73&tbnw=99&hl=en&start=33&prev=/images%3Fq%3DOvarian%2BCancer%26start%3D20%26svnum%3D10%26hl%3Den%26lr%3D%26sa%3DN • Treatment of Ovarian Cancer at Mayo Clinic. [internet]; c 2001-2006. [cited 2006 Jan. 31]. Available from:http://images.google.com/imgres?imgurl=http://www.mayoclinic.org/ovarian-cancer/images/ovariantumor.jpg&imgrefurl=http://www.mayoclinic.org/ovarian-cancer/&h=205&w=162&sz=13&tbnid=-h0xk4tQxD-H4M:&tbnh=100&tbnw=79&hl=en&start=2&prev=/images%3Fq%3DOvarian%2BCancer%26svnum%3D10%26hl%3Den%26lr%3D%26sa%3DN