The Neurobiology of Addiction. Kim Edward Light, Ph.D. Professor, College of Pharmacy University of Arkansas for Medical Sciences. Objectives. Review definitions for abuse, dependance, and addiction.
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Kim Edward Light, Ph.D.
Professor, College of Pharmacy
University of Arkansas for Medical Sciences
The American Society of Addiction Medicine (ASAM), the American Academy of Pain Medicine (AAPM), and the American Pain Society (APS)
Addiction is a primary, chronic, neurobiological disease, with genetic, psychosocial, and environmental factors influencing its development and manifestations.
Slide image from NIDA
Prefrontal Orbitofrontal Cortex
Cognition, Judgment, Planning, Inhibitions, Personality,
alterations in the ability of the PFC, OFC, ACG to process and appropriately respond to information identified as important by DA neurotransmission from the reward pathway.