Finding Promoters other important genomic sequences. Lecture 10. Introduction. Purpose of Promoter analysis Finding Prokaryotic promoters Finding Eukaryotic promoters Two basic approaches to finding promoters and other regulatory elements
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Adapted Understanding bioinformatics 9.3
The figure below illustrates a number of eukaryotic promoters and illustrates the variability. [klug 7thed] . However it also illustrates the common features: TATA box…
Figure A and B show the results of patterns associated with the TATA box
Note a score of -8.16 must be obtained to classify it as a TATA box “region”
Figure C and D are associated with the DNA CAP signals (CAP is a transcriptional activator). “do not confuse it with the 5’ RNA Cap (Cap and poly A tail )”