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Understanding the PTP1B Active Site Architecture

Explore the intricate details of the PTP1B active site including key components like Q-loop and Asp181. Courtesy of Dr. Robert Del Vecchio.

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Understanding the PTP1B Active Site Architecture

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  1. The architecture of the PTP1B active site Phosphotyrosine (Substrate) Phe180 Gln262 Q-loop pTyr-loop Tyr46 Asp181 WPD-loop PTP-loop Arg221 Cys215 http://ptp.cshl.edu or http://science.novonordisk.com/ptp Courtesy of Dr. Robert Del. Vecchio

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