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ERYTHROPOEISIS

ERYTHROPOEISIS. RBC. Basophilic. Polychroma-. Orthochroma-. Hemocytoblast. Proerythroblast. Erythroblast. tophilic. tophilic. Nuclear. Reticulocyte. Erythroblast. Erythroblast. Extrusion. 1. dispersed. 1. clumped. 1. condensed. 1. condensed. 1. anucleate. Pluripotential.

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ERYTHROPOEISIS

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  1. ERYTHROPOEISIS RBC Basophilic Polychroma- Orthochroma- Hemocytoblast Proerythroblast Erythroblast tophilic tophilic Nuclear Reticulocyte Erythroblast Erythroblast Extrusion 1. dispersed 1. clumped 1. condensed 1. condensed 1. anucleate Pluripotential chromatin eccentric chromatin chromatin Stem Cell nucleus 2. spherical 2. grey-green 2. nucleoli 2. no 2. pink cytoplasm 3. slight nucleoli cytoplasm basophilia (hemoglobin 3. cytoplasmic 3. maximum (free ribosomes) synthesis) basophilia basophilia

  2. Erythropoeisis- Several Stages

  3. MYELOPOEISIS (granulopoeisis) Hemocytoblast Myeloblast (multipotential) (multipotential) Promyelocyte (multipotential) 1. loss of cytoplasmic basophilia 2. dispersed chromatin Eosinophilopoeisis Neutrophilopoeisis Basophilopoeisis

  4. EOSINOPHILOPOEISIS Eosinophilic Eosinophilic Eosinophil Myelocyte Metamyelocyte (band cell) Specific and Metachromatic Granules

  5. Eosinophilopoeisis- Several Stages

  6. NEUTROPHILOPOEISIS NEUTROPHILIC NEUTROPHILIC MYELOCYTE METAMYELOCYTE NEUTROPHIL

  7. MYELOPOEISIS (Several Stages) Nutrophilic Band and Neutrophilic and Eosinophilic Band Cells Eosinophilic Metamyelocyte

  8. BASOPHILOPOEISIS Basophilic Basophilic Myelocyte Basophil Metamyelocyte

  9. THROMBOPOEISIS Endomytosis (w/o karyokinesis Hemocytoblast (w/o cytokinesis) Reserve Megakaryocyte (megakaryoblast) Platelet-Forming Megakaryocyte Residual Megakaryocyte Platelet-Shedding Platelets (fusion of plasma membrane)

  10. MEGAKARYOCYTES

  11. BONE MARROW Decalcified Bone and Marrow Marrow Cavity Fat Cells Bone

  12. Marrow Endothelial Cells Megakaryocyte Diapedesis Adipocyte Endothelial Discontinuity Blood Sinusoid Reticular Hemopoetic Fibers Compartment

  13. Bone Marrow Bone Marrow in Decalcified Bone Bone Marrow Smear

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