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This study explores the close relationship between Dendritic Cells (DDCs) and cutaneous nerves, highlighting the reliance on Nav1.8+ nociceptors for IMQ-induced IL-23 production. The findings shed light on the intricate mechanisms governing immune responses in the skin.
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DDCs are closely associated with cutaneous nerves and depend on Nav1.8+ nociceptors for IMQ-induced IL-23 production. L Riol-Blancoet al. Nature 000, 1-5 (2014) doi:10.1038/nature13199