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Forward Looking Statements

Forward Looking Statements.

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Forward Looking Statements

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  1. Forward Looking Statements Statements about the future expectations of Scivanta Medical Corporation (the “Company”) and all other statements in this document other than historical facts are forward looking statements within the meaning of Section 27A of the Securities Act of 1933, as amended, and Section 21E of the Securities Exchange Act of 1934, as amended, and as that term is defined in the Private Securities Litigation Reform Act of 1995. Such statements are subject to certain risks, trends and uncertainties that could cause actual results to differ materially from expected results. Among these risks, trends and uncertainties are economic conditions both generally and in the industries in which the Company may participate; competition within the Company’s chosen industries, including competition from much larger competitors; technological advances; available capital; regulatory approvals and failure by the Company to successfully develop or acquire products and form new business relationships. The Company intends that such forwarding-looking statements shall be subject to the safe harbors created thereby. Since these statements involve risks and uncertainties and are subject to change at any time, the Company's actual results could differ materially from expected results.

  2. Scivanta’sStrategy • Acquire and develop medical technologies and products offering advantages over existing procedures and treatments • Focus on medical devices and other proprietary technologies or patented products • Seek patented renewable/disposable products: catalyst for repeat sales • High margin business model focused on technologies that are capable of being sold in a medical specialty or niche market

  3. Scivanta’s Current Technology The Hickey Cardiac Monitoring System (HCMS) • Developed at the University of Buffalo by Donald D. Hickey, MD • A system consisting of a monitor and disposable double-balloon esophageal catheter • Provides data similar to Swan-Ganz Catheter (pulmonary artery catheter or PAC) • Features and attributes that should expand use beyond the intensive care unit, especially in the surgical/anesthesia arena • Minimally-invasive, does not require the expense of an intensive care unit or placement by a physician

  4. The HCMS Catheter • Minimally invasive, two-balloon esophageal catheter • Compatible with continuous, long-term cardiac performance monitoring • Injection molded • Disposable • Sterility not required • Low production cost

  5. Basis of HCMS Technology: Unique Proximity of Esophagus and Heart Left Atrium Esophagus CAT Scan

  6. The HCMS Catheter Positioning • Positioning in the esophagus capitalizes on the unique anatomic relationship of the left atrium and aortic arch • Wall motion in the left atrium and aorta generate pressure change in the two balloons • These signals, along with data from an electrocardiogram, phonocardiogram and automated blood pressure cuff, are transmitted to the monitoring system, and converted into real-time clinical information

  7. Measurements Provided by the HCMS • Mean left atrial pressure (LAP) • Left ventricular contractility • Resting esophageal pressure (intrapleural pressure) • Mean left atrial transmural pressure • Systolic time intervals (pre-ejection period and left ventricular ejection time) • Two measures of diastolic dysfunction • Cardiac output by pulse contour method • Arterial pulse wave velocity • Continuous phonocardiography with audio output and visual display • Electrocardiogram • Blood pressure

  8. Systolic Time Intervals

  9. Swan-Ganz Data

  10. HCMS Data

  11. Operation of the HCMS • Rapid insertion and positioning by non-physician personnel • Minimally invasive esophageal route • Monitor the patient anywhere - not restricted to the ICU • Monitor the patient at continuous intervals • Minimal risk of systemic infection

  12. HCMS Product Features Base Unit • Instantaneous analysis and display of cardiac performance • Proprietary software algorithms • Moderate cost Other Features • Disposable catheter contains no metal components - may be used in MRI • Allows for phonocardiogram unaffected by typical surrounding noise (may be displayed graphically on monitor) • Integrated electrocardiogram and blood pressure measurement • 11 U.S. patents with corresponding patents in major international markets - approximately 10 years remaining on the principal patent

  13. HCMS vs. Swan-Ganz Comparative Outputs: HCMS Swan-Ganz Features X X CardiacOutput LeftAtrial Pressure X X Left Ventricular Contractility during Isovolumic Contraction X X LeftAtrialTransmural Pressure X PleuralPressure

  14. Market Opportunity • $500 million for all hemodynamic monitoring sales as of 2006 • PACs annual sales worldwide exceed $250 million – Edwards Lifesciences is the PAC market leader • Since the HCMS can be used outside of the ICU and is minimally invasive, the HCMS has market opportunities beyond the current PAC market which include: surgical settings where anesthesia is used; emergency rooms, out-patient and in-office monitoring of cardiac patients; post-operation monitoring of cardiac-challenged patients. • Non-ICU utilization is estimated by the Company to increase the potential market by two-to three fold, to $1.0 - 1.5 billion

  15. Treatment of Congestive Heart Failure • Measurement of left ventricular contractility during isovolumic contraction is potentially a new standard for guiding the treatment of congestive heart failure (CHF) • 4.9 million patients in US experience CHF, growing at 400,000 annually • $325 billion direct and indirect costs associated with cardiovascular disease in the year 2000 • CHF and related disease are the leading reason for emergency department admissions • 13% of all hospital visits involve CHF

  16. Scivanta’s Planned Approach to Market • Launch HCMS into the hospital setting • Introduce to anesthesiologists in surgical settings where patients have risks for a cardiac event (i.e. surgery involving the elderly and procedures involving significant fluid shift) • In-hospital monitoring of cardiac-challenged patients in non-surgical situations • Introduction of the HCMS to emergency departments • Launch HCMS in the physicians office and out-patient centers • Out-patient monitoring of CHF and other cardiac patients • Make available for out-patient surgeries

  17. Product Development and Regulatory Status • Initial prototypes have been patient tested • Alpha units to be completed in September 2008 • IRB has approved clinical study to commence in late September 2008 • File 510K application in 2008 • Expected U.S. market launch in March 2009

  18. Proposed Distribution and Service • Partner with third party distribution companies for all major markets • Attractive distribution model (base unit monitor and disposable catheter) • Moderately priced base unit and catheter • Service via depot method

  19. Development Team • Ethox International, Inc. (Buffalo, NY) is developing the catheter component of the HCMS • Applied Sciences Group (Buffalo, NY) is developing the software component of the HCMS • Sparton Medical Systems (DeLeon Springs, FL) is developing the hardware component of the HCMS • Rivertek Medical Systems (St. Paul, MN) is managing the development of the HCMS • In connection with the University of Buffalo and Ethox, $750,000 of development funding has been secured through the State of New York.

  20. Management David R. LaVance, Chairman, President, and Chief Executive Officer Mr. LaVance became the Company’s President and Chief Executive Officer and the Chairman of its Board of Directors on March 21, 2003. He also is the President and co-founder of Century Capital Associates LLC, which was founded in 1997. From 1995 through 1997 Mr. LaVance was a Managing Director of KPMG Health Ventures, an advisory group providing investment banking services to healthcare service providers. Before joining KPMG Health Ventures, Mr. LaVance was a founder of Physicians Data Corporation, a health informatics company formed in 1994, and served as the President of Nuclear Care, Inc., a nuclear imaging clinical services provider from 1992 through 1995. Before founding Nuclear care, Mr. LaVance held a series of operating positions with Dornier MedTech America, Inc., a medical device company that specializes in lithotriptors and other medical devices, ultimately serving as the President of Dornier MedTech in Japan. Mr. LaVance currently is a member of the Board of Directors of Hologic, Inc. (NASDAQ: HOLX), a medical device company specializing in women’s health. Mr. LaVance received a B.A. degree from Furman University and a J.D. degree from Washington College of Law of the American University. Thomas S. Gifford, Executive Vice President, Secretary, and Chief Financial Officer Mr. Gifford became the Company’s Executive Vice President, Chief Financial Officer (Treasurer) and a director on March 21, 2003. He later became the Secretary of the Company on July 22, 2003. Mr. Gifford is also the Vice President and co-founder of Century Capital Associates LLC. He is a licensed attorney in New York and New Jersey and is a Certified Public Accountant. He was formerly a Manager and Associate Director of KPMG Health Ventures. Prior to KPMG Health Ventures, Mr. Gifford was an accountant for KPMG Peat Marwick LLP from 1990 through 1994, where he provided auditing and financial due diligence services to various publicly traded and privately held emerging technology companies. Mr. Gifford currently serves on the Board of Directors of Maloy Risk Services, Inc., a privately held insurance brokerage. Mr. Gifford received a B.S. degree from Rutgers University and a J.D. degree from Seton Hall University School of Law.

  21. Board of Directors Richard E. Otto Mr. Otto was elected as a director of the Company on May 6, 2003. He has been a consultant since June 2007. Beginning January 2002, Mr. Otto served as the Chief Executive Officer and a director of Corautus Genetics Inc., a publicly traded biopharmaceutical company and its predecessor Vascular Genetics Inc., until June 2007 when Corautus merged with VIA Pharmaceuticals, Inc., a publicly traded biotechnology company (NASDAQ: VIAP). From June 1995 through April 1998, he was Chief Executive Officer and director of CardioDynamics International Corporation (NASDAQ: CDIS), a publicly traded company that develops, manufactures and markets noninvasive heart-monitoring devices. Mr. Otto has served as a consultant to the founder of WebMD and Cardiac Pacemakers Inc. (now a Guidant company). Mr. Otto also held positions at Intermedics, Inc., Medtronic Inc., and Eli Lilly and Company. Mr. Otto currently serves as a director of ImaRx Therapeutics, Inc. (NASDAQ: IMRX), a publicly traded biopharmaceutical company focused on the development and commercialization of therapies for vascular disorders. He received a B.S. degree from the University of Georgia. Lawrence M. Levy Mr. Levy was elected as a director of the Company on March 15, 2007. He has been Senior Counsel at Brown Rudnick Berlack Israels LLP, an international law firm, since February, 2005, and for more than 30 years before that, had been a partner at Brown Rudnick, specializing in Corporate and Securities Law. Mr. Levy is a director of Hologic, Inc. (NASDAQ: HOLX), and was Secretary of Hologic from 1985 until 2005. Mr. Levy is also a director of Option N.V. of Belgium, and the Facing History and Ourselves National Foundation. Mr. Levy received a B.A. from Yale University and a LLB from Harvard Law School. Anthony Giordano III Mr. Giordano was elected as a director of the Company on March 15, 2007. He has been the Executive Vice President and Chief Financial Officer of Central Jersey Bancorp since 1998, the inception of the bank. Before joining Central Jersey Bancorp, Mr. Giordano served at PNC Bank/Midlantic Bank from 1994 to 1998 and at Shadow Lawn Savings Bank from 1988 to 1994. Mr. Giordano has served as a Councilman for the city of Long Branch, NJ, from 1994 to the present. He also is a member of the Boards of Directors of the Kean University Foundation and the United Way of Monmouth County. Mr. Giordano received a B.S. in Finance from Kean University and an MBA from Monmouth University.

  22. Stock Information a/o 9/1/08 Stock Symbol SCVM Total Shares Outstanding 25,850,444 Potential Dilutive Shares Outstanding 4,561,018 Shares Outstanding Held By Affiliates 7,725,000 Float (approximate) 15,623,500

  23. HCMS Product Summary • Large market opportunity in excess of $1 billion • Razor/razor blade model • Patent-protected technology • Catheter can be rapidly inserted and positioned by a non-physician • Monitor patient in any clinical setting - not limited to ICU • Monitor the patient anytime - the catheter does not need to be removed for eating, drinking or sleeping • Future expansion into the physician office to address the CHF market

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